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Cytokine-Mediated Alterations of Human Cardiac Fibroblast's Secretome.
Bräuninger H, Thottakara T, Schön J, Voss S, Dhople V, Warnke S, Scherschel K, Schrage B, Kirchhof P, Blankenberg S, Völker U, Westermann D, Hammer E, Lindner D. Bräuninger H, et al. Among authors: thottakara t. Int J Mol Sci. 2021 Nov 12;22(22):12262. doi: 10.3390/ijms222212262. Int J Mol Sci. 2021. PMID: 34830141 Free PMC article.
Lipid metabolism drives allele-specific early-stage hypertrophic cardiomyopathy.
Vaniya A, Karlstaedt A, Gulkok DA, Thottakara T, Liu Y, Fan S, Eades H, Fukunaga R, Vernon HJ, Fiehn O, Roselle Abraham M. Vaniya A, et al. Among authors: thottakara t. bioRxiv [Preprint]. 2023 Nov 15:2023.11.10.564562. doi: 10.1101/2023.11.10.564562. bioRxiv. 2023. PMID: 38014251 Free PMC article. Preprint.
S100A4 as a Target of the E3-Ligase Asb2β and Its Effect on Engineered Heart Tissue.
Braumann S, Thottakara T, Stücker S, Reischmann-Düsener S, Krämer E, Groß J, Hirt MN, Doroudgar S, Carrier L, Friedrich FW. Braumann S, et al. Among authors: thottakara t. Front Physiol. 2018 Sep 19;9:1292. doi: 10.3389/fphys.2018.01292. eCollection 2018. Front Physiol. 2018. PMID: 30283351 Free PMC article.
The E3 ubiquitin ligase Asb2β is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation.
Thottakara T, Friedrich FW, Reischmann S, Braumann S, Schlossarek S, Krämer E, Juhr D, Schlüter H, van der Velden J, Münch J, Patten M, Eschenhagen T, Moog-Lutz C, Carrier L. Thottakara T, et al. J Mol Cell Cardiol. 2015 Oct;87:214-24. doi: 10.1016/j.yjmcc.2015.08.020. Epub 2015 Sep 3. J Mol Cell Cardiol. 2015. PMID: 26343497