[Clinical study of effect of tianzhi granule on senile vascular demetia]

Zhongguo Zhong Yao Za Zhi. 2003 Jan;28(1):73-7.
[Article in Chinese]

Abstract

Objective: To investigate the clinical effect of Tianzhi Granule (TZK) on senile vascular dementia (VaD), which is classified as sthenia of liver-yang.

Method: Two hundred VaD patients were treated with TZK (0.5 g/bag), which was taken one bag each, three times a day. The treatment course was one month and they were treated for rwo courses.

Result: TZK could remarkably increase gnosia and activity, with no striking difference from that of positive control group (P > 0.05). Simultaneously, TZK could significantly improve the clinical syndrome of traditional Chinese medicine and viability. It could also drastically reduce the whole blood and plasma viscosity and improve erythrodegeneration and abnormality of aggregation index in the abnormal blood viscosity patients.

Conclusion: TMC has certain effects on senile VaD.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Blood Viscosity / drug effects
  • Dementia, Vascular / blood
  • Dementia, Vascular / drug therapy*
  • Double-Blind Method
  • Drug Combinations
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / therapeutic use*
  • Erythrocyte Aggregation / drug effects
  • Erythrocyte Deformability / drug effects
  • Humans
  • Medicine, Chinese Traditional
  • Middle Aged
  • Multicenter Studies as Topic
  • Phytotherapy*
  • Plants, Medicinal* / chemistry
  • Recognition, Psychology / drug effects

Substances

  • Drug Combinations
  • Drugs, Chinese Herbal