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Synthesis, solubility, plasma stability, and pharmacological evaluation of novel sulfonylhydrazones designed as anti-diabetic agents.
Zapata-Sudo G, da Costa Nunes IK, Araujo JS, da Silva JS, Trachez MM, da Silva TF, da Costa FP, Sudo RT, Barreiro EJ, Lima LM. Zapata-Sudo G, et al. Among authors: da silva tf. Drug Des Devel Ther. 2016 Sep 9;10:2869-2879. doi: 10.2147/DDDT.S108327. eCollection 2016. Drug Des Devel Ther. 2016. PMID: 27672310 Free PMC article.
In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N-Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis.
Silva DKC, Teixeira JS, Moreira DRM, da Silva TF, Barreiro EJL, de Freitas HF, Pita SSDR, Teles ALB, Guimarães ET, Soares MBP. Silva DKC, et al. Among authors: da silva tf. Front Pharmacol. 2020 Dec 16;11:590544. doi: 10.3389/fphar.2020.590544. eCollection 2020. Front Pharmacol. 2020. PMID: 33390966 Free PMC article.
Potent immunosuppressive activity of a phosphodiesterase-4 inhibitor N-acylhydrazone in models of lipopolysaccharide-induced shock and delayed-type hypersensitivity reaction.
Guimarães ET, Dos Santos TB, Silva DKC, Meira CS, Moreira DRM, da Silva TF, Salmon D, Barreiro EJ, Soares MBP. Guimarães ET, et al. Among authors: da silva tf. Int Immunopharmacol. 2018 Dec;65:108-118. doi: 10.1016/j.intimp.2018.09.047. Epub 2018 Oct 9. Int Immunopharmacol. 2018. PMID: 30312879