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Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling.
Cicali B, Lingineni K, Cristofoletti R, Wendl T, Hoechel J, Wiesinger H, Chaturvedula A, Vozmediano V, Schmidt S. Cicali B, et al. Among authors: wendl t. CPT Pharmacometrics Syst Pharmacol. 2021 Jan;10(1):48-58. doi: 10.1002/psp4.12572. Epub 2020 Dec 13. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33217171 Free PMC article.
A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions.
Frechen S, Solodenko J, Wendl T, Dallmann A, Ince I, Lehr T, Lippert J, Burghaus R. Frechen S, et al. Among authors: wendl t. CPT Pharmacometrics Syst Pharmacol. 2021 Jun;10(6):633-644. doi: 10.1002/psp4.12636. Epub 2021 May 24. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33946131 Free PMC article.
Application of Physiologically-Based and Population Pharmacokinetic Modeling for Dose Finding and Confirmation During the Pediatric Development of Moxifloxacin.
Willmann S, Frei M, Sutter G, Coboeken K, Wendl T, Eissing T, Lippert J, Stass H. Willmann S, et al. Among authors: wendl t. CPT Pharmacometrics Syst Pharmacol. 2019 Sep;8(9):654-663. doi: 10.1002/psp4.12446. Epub 2019 Aug 7. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31310051 Free PMC article.
Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small-Molecule Compounds in Children.
Ince I, Dallmann A, Frechen S, Coboeken K, Niederalt C, Wendl T, Block M, Meyer M, Eissing T, Burghaus R, Lippert J, Willmann S, Schlender JF. Ince I, et al. Among authors: wendl t. J Clin Pharmacol. 2021 Jun;61 Suppl 1(Suppl 1):S70-S82. doi: 10.1002/jcph.1869. J Clin Pharmacol. 2021. PMID: 34185905 Free PMC article.
18 results