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NLRP10 Affects the Stability of Abin-1 To Control Inflammatory Responses.
Mirza N, Sowa AS, Lautz K, Kufer TA. Mirza N, et al. J Immunol. 2019 Jan 1;202(1):218-227. doi: 10.4049/jimmunol.1800334. Epub 2018 Dec 3. J Immunol. 2019. PMID: 30510071
The NLR family consists of 22 human proteins with a conserved structure containing a central oligomerization NACHT domain, an N-terminal interaction domain, and a variable number of C-terminal leucine-rich repeats. ...In this study, we identify Abin-1, a negative regulator …
The NLR family consists of 22 human proteins with a conserved structure containing a central oligomerization NACHT domain, an N-termi …
Pulmonary inflammation induced by low-dose particulate matter exposure in mice.
Chan YL, Wang B, Chen H, Ho KF, Cao J, Hai G, Jalaludin B, Herbert C, Thomas PS, Saad S, Oliver BGG. Chan YL, et al. Am J Physiol Lung Cell Mol Physiol. 2019 Sep 1;317(3):L424-L430. doi: 10.1152/ajplung.00232.2019. Epub 2019 Jul 31. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 31364371 Free PMC article.
At 5 mug, PM(10) exposure increased lymphocytes and macrophages in BAL fluid. Increased NACHT, LRR and PYD domains-containing protein 3 (NLRP3) and IL-1beta production occurred following PM(10) exposure. ...
At 5 mug, PM(10) exposure increased lymphocytes and macrophages in BAL fluid. Increased NACHT, LRR and PYD domains-containing protein …
Novel therapeutic insights into the treatment of pericarditis: Targeting the innate immune system.
Vecchié A, Bonaventura A, Golino M, Thomas G, Abbate A. Vecchié A, et al. J Cardiovasc Pharmacol. 2024 Feb 29. doi: 10.1097/FJC.0000000000001553. Online ahead of print. J Cardiovasc Pharmacol. 2024. PMID: 38422218
Current evidence highlights the central role played by interleukin 1 (IL-1) and NLRP3 (NACHT, leucine-rich repeat, and pyrin domain-containing protein 3) in idiopathic recurrent pericarditis. ...
Current evidence highlights the central role played by interleukin 1 (IL-1) and NLRP3 (NACHT, leucine-rich repeat, and pyrin domain-c …
Specific Surface Modifications of Silica Nanoparticles Diminish Inflammasome Activation and In Vivo Expression of Selected Inflammatory Genes.
Marzaioli V, Groß CJ, Weichenmeier I, Schmidt-Weber CB, Gutermuth J, Groß O, Alessandrini F. Marzaioli V, et al. Nanomaterials (Basel). 2017 Oct 30;7(11):355. doi: 10.3390/nano7110355. Nanomaterials (Basel). 2017. PMID: 29084176 Free PMC article.
Here, murine bone marrow-derived dendritic (BMDC) and a mouse model of mild allergic inflammation were used to study inflammasome activation and lung inflammation. Our results showed that SiO2 plain NPs induced NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflam …
Here, murine bone marrow-derived dendritic (BMDC) and a mouse model of mild allergic inflammation were used to study inflammasome activation …