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A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.
Thomas SP, Domm JM, van Vloten JP, Xu L, Vadivel A, Yates JGE, Pei Y, Ingrao J, van Lieshout LP, Jackson SR, Minott JA, Achuthan A, Mehrani Y, McAusland TM, Zhang W, Karimi K, Vaughan AE, de Jong J, Kang MH, Thebaud B, Wootton SK. Thomas SP, et al. Mol Ther. 2023 Dec 6;31(12):3457-3477. doi: 10.1016/j.ymthe.2023.10.002. Epub 2023 Oct 7. Mol Ther. 2023. PMID: 37805711 Free article.
Mood and Anxiety Disorders and Suicidality in Patients With Newly Diagnosed Focal Epilepsy: An Analysis of a Complex Comorbidity.
Kanner AM, Saporta AS, Kim DH, Barry JJ, Altalib H, Omotola H, Jette N, O'Brien TJ, Nadkarni S, Winawer MR, Sperling M, French JA, Abou-Khalil B, Alldredge B, Bebin M, Cascino GD, Cole AJ, Cook MJ, Detyniecki K, Devinsky O, Dlugos D, Faught E, Ficker D, Fields M, Gidal B, Gelfand M, Glynn S, Halford JJ, Haut S, Hegde M, Holmes MG, Kalviainen R, Kang J, Klein P, Knowlton RC, Krishnamurthy K, Kuzniecky R, Kwan P, Lowenstein DH, Marcuse L, Meador KJ, Mintzer S, Pardoe HR, Park K, Penovich P, Singh RK, Somerville E, Szabo CA, Szaflarski JP, Lin Thio KL, Trinka E, Burneo JG; Human Epilepsy Project. Kanner AM, et al. Neurology. 2023 Mar 14;100(11):e1123-e1134. doi: 10.1212/WNL.0000000000201671. Epub 2022 Dec 20. Neurology. 2023. PMID: 36539302 Free PMC article.
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency.
Kang MH, van Lieshout LP, Xu L, Domm JM, Vadivel A, Renesme L, Mühlfeld C, Hurskainen M, Mižíková I, Pei Y, van Vloten JP, Thomas SP, Milazzo C, Cyr-Depauw C, Whitsett JA, Nogee LM, Wootton SK, Thébaud B. Kang MH, et al. Nat Commun. 2020 Aug 6;11(1):3929. doi: 10.1038/s41467-020-17577-8. Nat Commun. 2020. PMID: 32764559 Free PMC article.
Modulation of Endothelial Bone Morphogenetic Protein Receptor Type 2 Activity by Vascular Endothelial Growth Factor Receptor 3 in Pulmonary Arterial Hypertension.
Hwangbo C, Lee HW, Kang H, Ju H, Wiley DS, Papangeli I, Han J, Kim JD, Dunworth WP, Hu X, Lee S, El-Hely O, Sofer A, Pak B, Peterson L, Comhair S, Hwang EM, Park JY, Thomas JL, Bautch VL, Erzurum SC, Chun HJ, Jin SW. Hwangbo C, et al. Circulation. 2017 Jun 6;135(23):2288-2298. doi: 10.1161/CIRCULATIONAHA.116.025390. Epub 2017 Mar 29. Circulation. 2017. PMID: 28356442 Free PMC article.