Structures and Bioactivities of Steroidal Saponins Isolated from the Genera Dracaena and Sansevieria

Molecules. 2021 Mar 29;26(7):1916. doi: 10.3390/molecules26071916.

Abstract

The species Dracaena and Sansevieria, that are well-known for different uses in traditional medicines and as indoor ornamental plants with air purifying property, are rich sources of bioactive secondary metabolites. In fact, a wide variety of phytochemical constituents have been isolated so far from about seventeen species. This paper has reviewed the literature of about 180 steroidal saponins, isolated from Dracaena and Sansevieria species, as a basis for further studies. Saponins are among the most characteristic metabolites isolated from the two genera. They show a great variety in structural motifs and a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-proliferative effects and, in most case, remarkable cytotoxic properties.

Keywords: Dracaena; Sansevieria; biological activities; cytotoxicity; phytochemical constituents; steroidal saponins.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Inflammatory Agents / chemistry
  • Antineoplastic Agents / chemistry
  • Dracaena / metabolism*
  • Molecular Structure
  • Phytochemicals / chemistry*
  • Plant Extracts / chemistry*
  • Sansevieria / metabolism*
  • Saponins / chemistry*

Substances

  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Antineoplastic Agents
  • Phytochemicals
  • Plant Extracts
  • Saponins