Transposable elements regulate thymus development and function.
Larouche JD, Laumont CM, Trofimov A, Vincent K, Hesnard L, Brochu S, Côté C, Humeau JF, Bonneil É, Lanoix J, Durette C, Gendron P, Laverdure JP, Richie ER, Lemieux S, Thibault P, Perreault C.
Larouche JD, et al.
Elife. 2024 Apr 18;12:RP91037. doi: 10.7554/eLife.91037.
Elife. 2024.
PMID: 38635416
Free PMC article.
This study highlights the diversity of interactions between TEs and the adaptive immune system. TEs are genetic parasites, and the two thymic cell types most affected by TEs (mTEcs and pDCs) are essential to establishing central T-cell tolerance. ...
This study highlights the diversity of interactions between TEs and the adaptive immune system. TEs are genetic parasites, and the tw …