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Tetrazole-based inhibitors of the bacterial enzyme N-succinyl-l,l-2,6-diaminopimelic acid desuccinylase as potential antibiotics.
DiPuma T Jr, Thabthimthong T, Kelley EH, Konczak K, Beulke M, Herbert C, S Habeeb Mohammad T, Starus A, Nocek B, Olsen KW, Holz RC, Becker DP. DiPuma T Jr, et al. Among authors: s habeeb mohammad t. Bioorg Med Chem Lett. 2023 Mar 1;83:129177. doi: 10.1016/j.bmcl.2023.129177. Epub 2023 Feb 9. Bioorg Med Chem Lett. 2023. PMID: 36764468
Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase.
Zhu W, Butrin A, Melani RD, Doubleday PF, Ferreira GM, Tavares MT, Habeeb Mohammad TS, Beaupre BA, Kelleher NL, Moran GR, Liu D, Silverman RB. Zhu W, et al. Among authors: habeeb mohammad ts. J Am Chem Soc. 2022 Mar 30;144(12):5629-5642. doi: 10.1021/jacs.2c00924. Epub 2022 Mar 16. J Am Chem Soc. 2022. PMID: 35293728 Free PMC article.
Correction to "Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase".
Zhu W, Butrin A, Melani RD, Doubleday PF, Ferreira GM, Tavares MT, Habeeb Mohammad TS, Beaupre BA, Kelleher NL, Moran GR, Liu D, Silverman RB. Zhu W, et al. Among authors: habeeb mohammad ts. J Am Chem Soc. 2023 May 3;145(17):9895-9896. doi: 10.1021/jacs.3c03364. Epub 2023 Apr 19. J Am Chem Soc. 2023. PMID: 37075548 No abstract available.