Wireless remote monitoring of glucose using a functionalized ZnO nanowire arrays based sensor

Sensors (Basel). 2011;11(9):8485-96. doi: 10.3390/s110908485. Epub 2011 Aug 29.

Abstract

This paper presents a prototype wireless remote glucose monitoring system interfaced with a ZnO nanowire arrays-based glucose sensor, glucose oxidase enzyme immobilized onto ZnO nanowires in conjunction with a Nafion® membrane coating, which can be effectively applied for the monitoring of glucose levels in diabetics. Global system for mobile communications (GSM) services like general packet radio service (GPRS) and Short Message Service (SMS) have been proven to be logical and cost effective methods for gathering data from remote locations. A communication protocol that facilitates remote data collection using SMS has been utilized for monitoring a patient's sugar levels. In this study, we demonstrate the remote monitoring of the glucose levels with existing GPRS/GSM network infra-structures using our proposed functionalized ZnO nanowire arrays sensors integrated with standard readily available mobile phones. The data can be used for centralized monitoring and other purposes. Such applications can reduce health care costs and allow caregivers to monitor and support to their patients remotely, especially those located in rural areas.

Keywords: Global System for Mobile Communications (GSM); Nafion® membrane; ZnO nanowires; data acquisition; electrochemical nanosensor; glucose oxidase; remote monitoring.

MeSH terms

  • Glucose / analysis*
  • Glucose Oxidase / chemistry*
  • Microscopy, Electron, Scanning
  • Nanowires*
  • Radio Waves*
  • Text Messaging
  • Zinc Oxide / chemistry*

Substances

  • Glucose Oxidase
  • Glucose
  • Zinc Oxide