Protective effect of the T112 PrP variant in sheep challenged with bovine spongiform encephalopathy.
Saunders GC, Lantier I, Cawthraw S, Berthon P, Moore SJ, Arnold ME, Windl O, Simmons MM, Andréoletti O, Bellworthy S, Lantier F.
Saunders GC, et al.
J Gen Virol. 2009 Oct;90(Pt 10):2569-2574. doi: 10.1099/vir.0.012724-0. Epub 2009 Jul 8.
J Gen Virol. 2009.
PMID: 19587133
Sequencing of the full PRNP gene open reading frame of BSE-susceptible and -resistant sheep indicated that, in the majority of Suffolk sheep, resistance was associated with an M112T PRNP variant (TARQ allele). A high proportion (47 of 49; 96%) of BSE-challenged wild-type ( …
Sequencing of the full PRNP gene open reading frame of BSE-susceptible and -resistant sheep indicated that, in the majority of Suffolk sheep …