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Page 1
Early effects of lasonolide a on pancreatic cancer cells.
Isbrucker RA, Guzmán EA, Pitts TP, Wright AE. Isbrucker RA, et al. Among authors: pitts tp. J Pharmacol Exp Ther. 2009 Nov;331(2):733-9. doi: 10.1124/jpet.109.155531. Epub 2009 Aug 19. J Pharmacol Exp Ther. 2009. PMID: 19692635 Free PMC article.
Isolation, synthesis, and biological activity of aphrocallistin, an adenine-substituted bromotyramine metabolite from the Hexactinellida sponge Aphrocallistes beatrix.
Wright AE, Roth GP, Hoffman JK, Divlianska DB, Pechter D, Sennett SH, Guzmán EA, Linley P, McCarthy PJ, Pitts TP, Pomponi SA, Reed JK. Wright AE, et al. Among authors: pitts tp. J Nat Prod. 2009 Jun;72(6):1178-83. doi: 10.1021/np900183v. J Nat Prod. 2009. PMID: 19459694 Free PMC article.
Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
Guzmán EA, Xu Q, Pitts TP, Mitsuhashi KO, Baker C, Linley PA, Oestreicher J, Tendyke K, Winder PL, Suh EM, Wright AE. Guzmán EA, et al. Among authors: pitts tp. Int J Cancer. 2016 Nov 1;139(9):2116-26. doi: 10.1002/ijc.30253. Epub 2016 Jul 19. Int J Cancer. 2016. PMID: 27376928 Free PMC article.
Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.
Paterson I, Dalby SM, Roberts JC, Naylor GJ, Guzmán EA, Isbrucker R, Pitts TP, Linley P, Divlianska D, Reed JK, Wright AE. Paterson I, et al. Among authors: pitts tp. Angew Chem Int Ed Engl. 2011 Mar 28;50(14):3219-23. doi: 10.1002/anie.201007719. Epub 2011 Mar 4. Angew Chem Int Ed Engl. 2011. PMID: 21374771 Free PMC article.
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