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Estimation of Process Model Parameters.
Deppe S, Frahm B, Hass VC, Hernández Rodríguez T, Kuchemüller KB, Möller J, Pörtner R. Deppe S, et al. Among authors: hernandez rodriguez t. Methods Mol Biol. 2020;2095:213-234. doi: 10.1007/978-1-0716-0191-4_12. Methods Mol Biol. 2020. PMID: 31858470
Digital Seed Train Twins and Statistical Methods.
Hernández Rodríguez T, Frahm B. Hernández Rodríguez T, et al. Adv Biochem Eng Biotechnol. 2021;176:97-131. doi: 10.1007/10_2020_137. Adv Biochem Eng Biotechnol. 2021. PMID: 32797269
View on a mechanistic model of Chlorella vulgaris in incubated shake flasks.
Kuhfuß F, Gassenmeier V, Deppe S, Ifrim G, Rodríguez TH, Frahm B. Kuhfuß F, et al. Among authors: rodriguez th. Bioprocess Biosyst Eng. 2022 Jan;45(1):15-30. doi: 10.1007/s00449-021-02627-2. Epub 2021 Oct 22. Bioprocess Biosyst Eng. 2022. PMID: 34677674 Free PMC article.
Predicting industrial-scale cell culture seed trains-A Bayesian framework for model fitting and parameter estimation, dealing with uncertainty in measurements and model parameters, applied to a nonlinear kinetic cell culture model, using an MCMC method.
Hernández Rodríguez T, Posch C, Schmutzhard J, Stettner J, Weihs C, Pörtner R, Frahm B. Hernández Rodríguez T, et al. Biotechnol Bioeng. 2019 Nov;116(11):2944-2959. doi: 10.1002/bit.27125. Epub 2019 Sep 2. Biotechnol Bioeng. 2019. PMID: 31347693