Portable Infrared-Based Glucometer Reinforced with Fuzzy Logic

Biosensors (Basel). 2023 Nov 20;13(11):991. doi: 10.3390/bios13110991.

Abstract

Diabetes mellitus (DM) is a chronic metabolic condition characterized by high blood glucose levels owing to decreased insulin production or sensitivity. Current diagnostic approaches for gestational diabetes entail intrusive blood tests, which are painful and impractical for regular monitoring. Additionally, typical blood glucose monitoring systems are restricted in their measurement frequency and need finger pricks for blood samples. This research study focuses on the development of a non-invasive, real-time glucose monitoring method based on the detection of glucose in human tears and finger blood using mid-infrared (IR) spectroscopy. The proposed solution combines a fuzzy logic-based calibration mechanism with an IR sensor and Arduino controller. This calibration technique increases the accuracy of non-invasive glucose testing based on MID absorbance in fingertips and human tears. The data demonstrate that our device has high accuracy and reliability, with an error rate of less than 3%, according to the EGA. Out of 360 measurements, 97.5% fell into zone A, 2.2% into zone B, and 0.3% into zone C of the Clarke Error Grid. This suggests that our device can give clinically precise and acceptable estimates of blood glucose levels without inflicting any harm or discomfort on the user.

Keywords: fuzzy logic; glucose monitoring; mid-infrared probe; tears.

MeSH terms

  • Blood Glucose / metabolism
  • Blood Glucose Self-Monitoring* / methods
  • Diabetes Mellitus, Type 2*
  • Fuzzy Logic
  • Glucose
  • Humans
  • Reproducibility of Results

Substances

  • Blood Glucose
  • Glucose

Grants and funding

This research received no external funding.