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Year Number of Results
2012 2
2013 1
2015 1
2017 2
2018 6
2019 6
2020 4
2021 7
2022 6
2023 10
2024 2

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Page 1
Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
Higashi-Kuwata N, Tsuji K, Hayashi H, Bulut H, Kiso M, Imai M, Ogata-Aoki H, Ishii T, Kobayakawa T, Nakano K, Takamune N, Kishimoto N, Hattori SI, Das D, Uemura Y, Shimizu Y, Aoki M, Hasegawa K, Suzuki S, Nishiyama A, Saruwatari J, Shimizu Y, Sukenaga Y, Takamatsu Y, Tsuchiya K, Maeda K, Yoshimura K, Iida S, Ozono S, Suzuki T, Okamura T, Misumi S, Kawaoka Y, Tamamura H, Mitsuya H. Higashi-Kuwata N, et al. Among authors: kobayakawa t. Nat Commun. 2023 Feb 25;14(1):1076. doi: 10.1038/s41467-023-36729-0. Nat Commun. 2023. PMID: 36841831 Free PMC article.
Low-molecular-weight anti-HIV-1 agents targeting HIV-1 capsid proteins.
Kobayakawa T, Yokoyama M, Tsuji K, Fujino M, Kurakami M, Onishi T, Boku S, Ishii T, Miura Y, Shinohara K, Kishihara Y, Ohashi N, Kotani O, Murakami T, Sato H, Tamamura H. Kobayakawa T, et al. RSC Adv. 2023 Jan 12;13(3):2156-2167. doi: 10.1039/d2ra06837k. eCollection 2023 Jan 6. RSC Adv. 2023. PMID: 36712613 Free PMC article.
Bivalent HIV-1 fusion inhibitors based on peptidomimetics.
Kobayakawa T, Ebihara K, Tsuji K, Kawada T, Fujino M, Honda Y, Ohashi N, Murakami T, Tamamura H. Kobayakawa T, et al. Bioorg Med Chem. 2020 Dec 15;28(24):115812. doi: 10.1016/j.bmc.2020.115812. Epub 2020 Oct 9. Bioorg Med Chem. 2020. PMID: 33157478
Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins.
Kobayakawa T, Yokoyama M, Tsuji K, Fujino M, Kurakami M, Boku S, Nakayama M, Kaneko M, Ohashi N, Kotani O, Murakami T, Sato H, Tamamura H. Kobayakawa T, et al. Biomolecules. 2021 Feb 3;11(2):208. doi: 10.3390/biom11020208. Biomolecules. 2021. PMID: 33546092 Free PMC article.
Development of anti-HBV agents targeting HBV capsid proteins.
Kobayakawa T, Amano M, Nakayama M, Tsuji K, Ishii T, Miura Y, Shinohara K, Yamamoto K, Matsuoka M, Tamamura H. Kobayakawa T, et al. RSC Med Chem. 2023 Aug 24;14(10):1973-1980. doi: 10.1039/d3md00258f. eCollection 2023 Oct 18. RSC Med Chem. 2023. PMID: 37859721
Soluble-type small-molecule CD4 mimics as HIV entry inhibitors.
Kobayakawa T, Konno K, Ohashi N, Takahashi K, Masuda A, Yoshimura K, Harada S, Tamamura H. Kobayakawa T, et al. Bioorg Med Chem Lett. 2019 Mar 1;29(5):719-723. doi: 10.1016/j.bmcl.2019.01.011. Epub 2019 Jan 11. Bioorg Med Chem Lett. 2019. PMID: 30665681
Potent and biostable inhibitors of the main protease of SARS-CoV-2.
Tsuji K, Ishii T, Kobayakawa T, Higashi-Kuwata N, Azuma C, Nakayama M, Onishi T, Nakano H, Wada N, Hori M, Shinohara K, Miura Y, Kawada T, Hayashi H, Hattori SI, Bulut H, Das D, Takamune N, Kishimoto N, Saruwatari J, Okamura T, Nakano K, Misumi S, Mitsuya H, Tamamura H. Tsuji K, et al. Among authors: kobayakawa t. iScience. 2022 Nov 18;25(11):105365. doi: 10.1016/j.isci.2022.105365. Epub 2022 Nov 1. iScience. 2022. PMID: 36338434 Free PMC article.
40 results