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Page 1
Bioanalysis of therapeutic monoclonal antibody by peptide adsorption-controlled LC-MS.
Hashii N, Tousaka Y, Arai K, Enoki Y, Fukuda S, Goda R, Inoue N, Kawabata M, Murata K, Nakatsuji M, Okuzono T, Shigeyama T, Tachiki H, Yamaguchi T, Yamane S, Yamaoka M, Saito Y, Ishii-Watabe A. Hashii N, et al. Among authors: okuzono t. Bioanalysis. 2021 Feb;13(4):265-276. doi: 10.4155/bio-2020-0262. Epub 2021 Feb 5. Bioanalysis. 2021. PMID: 33543661
Development and multicenter validation of an LC-MS-based bioanalytical method for antisense therapeutics.
Sun Y, Nitta SI, Saito K, Hosogai R, Nakai K, Goda R, Shimizu H, Fujita H, Kakehi M, Murata K, Yamaguchi T, Okuzono T, Yamane S, Kawabata M, Matsunuma T, Takahara K, Kato N, Yamada M, Yoshida T, Inoue T, Saito Y. Sun Y, et al. Among authors: okuzono t. Bioanalysis. 2022 Sep;14(18):1213-1227. doi: 10.4155/bio-2022-0126. Epub 2022 Nov 21. Bioanalysis. 2022. PMID: 36408704
Establishment of the Global SEND Alliance (G-SEND) in Japan and efficient creation of electronic SEND datasets between CROs.
Anzai T, Matsuyama T, Wasko M, Hatakeyama H, Horikawa SI, Anzai R, Iwata H, Imai N, Mizuhashi F, Tsuboi M, Okuzono T, Takagi H, Cho H, Rong BTS, Masaki F, Nakae D. Anzai T, et al. Among authors: okuzono t. J Toxicol Pathol. 2019 Apr;32(2):119-126. doi: 10.1293/tox.2018-0066. Epub 2019 Mar 2. J Toxicol Pathol. 2019. PMID: 31092979 Free PMC article.
Human plasma concentration-time profiles of troglitazone and troglitazone sulfate simulated by in vivo experiments with chimeric mice with humanized livers and semi-physiological pharmacokinetic modeling.
Ito S, Kamimura H, Yamamoto Y, Chijiwa H, Okuzono T, Suemizu H, Yamazaki H. Ito S, et al. Among authors: okuzono t. Drug Metab Pharmacokinet. 2020 Dec;35(6):505-514. doi: 10.1016/j.dmpk.2020.07.004. Epub 2020 Jul 30. Drug Metab Pharmacokinet. 2020. PMID: 32962912
Simulation of human plasma concentration-time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite using humanized chimeric mice and semi-physiological pharmacokinetic modeling.
Kamimura H, Ito S, Chijiwa H, Okuzono T, Ishiguro T, Yamamoto Y, Nishinoaki S, Ninomiya SI, Mitsui M, Kalgutkar AS, Yamazaki H, Suemizu H. Kamimura H, et al. Among authors: okuzono t. Xenobiotica. 2017 May;47(5):382-393. doi: 10.1080/00498254.2016.1199063. Epub 2016 Jul 7. Xenobiotica. 2017. PMID: 27389028
14 results