City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model

PLoS One. 2020 Aug 28;15(8):e0238411. doi: 10.1371/journal.pone.0238411. eCollection 2020.

Abstract

Background: In December 2019, an outbreak of COVID-19 epidemic occurred in Wuhan, China and infection spread rapidly around the world. To limit the rapid spread locally and nationwide, the Chinese government locked down Wuhan city on January 23 and began implementing nationwide intensive community screening on February 16.

Method: To assess the effectiveness of city lockdown and intensive community screening, we built a modified SIR model by introducing an α value into the classic SIR model. The α value represents the proportion of infected individuals who are not effectively isolated from susceptible individuals at a given time point.

Results: The accuracy of the modified SIR model was validated using data from Guangdong and Zhejiang provinces. The lockdown of Wuhan city substantially reduced the α value for the rest of China excluding Hubei province, while only slightly reducing the α value for the city itself. Intensive community screening rapidly reduced the α value for Wuhan.

Conclusion: City lockdown was efficient in controlling the spread of the epidemic from Wuhan to the rest of the country. Nationwide intensive community screening was extremely effective in suppressing the spread locally within Wuhan city. These experiences should urgently be shared with other countries to help halt the progressing worldwide pandemic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Betacoronavirus
  • COVID-19
  • China / epidemiology
  • Cities
  • Communicable Disease Control / methods*
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / prevention & control*
  • Humans
  • Mass Screening
  • Models, Theoretical
  • Pandemics / prevention & control*
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / prevention & control*
  • SARS-CoV-2
  • Social Isolation

Grants and funding

This paper presents independent research that was funded by the National Natural Science Foundation of China (Grant No. 81570374). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.