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Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion.
Eser TM, Baranov O, Huth M, Ahmed MIM, Deák F, Held K, Lin L, Pekayvaz K, Leunig A, Nicolai L, Pollakis G, Buggert M, Price DA, Rubio-Acero R, Reich J, Falk P, Markgraf A, Puchinger K, Castelletti N, Olbrich L, Vanshylla K, Klein F, Wieser A, Hasenauer J, Kroidl I, Hoelscher M, Geldmacher C. Eser TM, et al. Nat Commun. 2023 May 24;14(1):2952. doi: 10.1038/s41467-023-38020-8. Nat Commun. 2023. PMID: 37225706 Free PMC article.
Studying temporal titre evolution of commercial SARS-CoV-2 assays reveals significant shortcomings of using BAU standardization for comparison.
Kroidl I, Winter S, Rubio-Acero R, Bakuli A, Geldmacher C, Eser TM, Déak F, Horn S, Zielke A, Ahmed MIM, Diepers P, Guggenbühl J, Frese J, Bruger J, Puchinger K, Reich J, Falk P, Markgraf A, Fensterseifer H, Paunovic I, Thomschke A, Pritsch M, Riess F, Saathoff E, Hoelscher M, Olbrich L, Castelletti N, Wieser A; KoCo19/ORCHESTRA Study Group. Kroidl I, et al. Among authors: eser tm. Virol J. 2023 Sep 1;20(1):200. doi: 10.1186/s12985-023-02167-z. Virol J. 2023. PMID: 37658454 Free PMC article.
SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Reincke SM, Yuan M, Kornau HC, Corman VM, van Hoof S, Sánchez-Sendin E, Ramberger M, Yu W, Hua Y, Tien H, Schmidt ML, Schwarz T, Jeworowski LM, Brandl SE, Rasmussen HF, Homeyer MA, Stöffler L, Barner M, Kunkel D, Huo S, Horler J, von Wardenburg N, Kroidl I, Eser TM, Wieser A, Geldmacher C, Hoelscher M, Gänzer H, Weiss G, Schmitz D, Drosten C, Prüss H, Wilson IA, Kreye J. Reincke SM, et al. Among authors: eser tm. Science. 2022 Feb 18;375(6582):782-787. doi: 10.1126/science.abm5835. Epub 2022 Jan 25. Science. 2022. PMID: 35076281 Free PMC article.
Enhanced Spike-specific, but attenuated Nucleocapsid-specific T cell responses upon SARS-CoV-2 breakthrough versus non-breakthrough infections.
Ahmed MIM, Diepers P, Janke C, Plank M, Eser TM, Rubio-Acero R, Fuchs A, Baranov O, Castelletti N, Kroidl I, Olbrich L, Bauer B, Wang D, Prelog M, Liese JG, Reinkemeyer C, Hoelscher M, Steininger P, Überla K, Wieser A, Geldmacher C. Ahmed MIM, et al. Among authors: eser tm. Front Immunol. 2022 Dec 13;13:1026473. doi: 10.3389/fimmu.2022.1026473. eCollection 2022. Front Immunol. 2022. PMID: 36582222 Free PMC article.
CD34T+ Humanized Mouse Model to Study Mucosal HIV-1 Transmission and Prevention.
Vanshylla K, Held K, Eser TM, Gruell H, Kleipass F, Stumpf R, Jain K, Weiland D, Münch J, Grüttner B, Geldmacher C, Klein F. Vanshylla K, et al. Among authors: eser tm. Vaccines (Basel). 2021 Feb 27;9(3):198. doi: 10.3390/vaccines9030198. Vaccines (Basel). 2021. PMID: 33673566 Free PMC article.
The interplay of viral loads, clinical presentation, and serological responses in SARS-CoV-2 - Results from a prospective cohort of outpatient COVID-19 cases.
Puchinger K, Castelletti N, Rubio-Acero R, Geldmacher C, Eser TM, Deák F, Paunovic I, Bakuli A, Saathoff E, von Meyer A, Markgraf A, Falk P, Reich J, Riess F, Girl P, Müller K, Radon K, Guggenbuehl Noller JM, Wölfel R, Hoelscher M, Kroidl I, Wieser A, Olbrich L; KoCo19 study group. Puchinger K, et al. Among authors: eser tm. Virology. 2022 Apr;569:37-43. doi: 10.1016/j.virol.2022.02.002. Epub 2022 Feb 18. Virology. 2022. PMID: 35245784 Free PMC article.
Impact of Omicron Variant Infection on Assessment of Spike-Specific Immune Responses Using the EUROIMMUN Quan-T-Cell SARS-CoV-2 Assay and Roche Elecsys Anti-SARS-CoV-2-S.
Ahmed MIM, Plank M, Castelletti N, Diepers P, Eser TM, Rubio-Acero R, Noreña I, Reinkemeyer C, Zapf D, Hoelscher M, Janke C, Wieser A, Geldmacher C, On Behalf Of The KoCo/Orchestra Study Group. Ahmed MIM, et al. Among authors: eser tm. Diagnostics (Basel). 2023 Mar 8;13(6):1024. doi: 10.3390/diagnostics13061024. Diagnostics (Basel). 2023. PMID: 36980332 Free PMC article.
Broad T Cell Targeting of Structural Proteins After SARS-CoV-2 Infection: High Throughput Assessment of T Cell Reactivity Using an Automated Interferon Gamma Release Assay.
Brand I, Gilberg L, Bruger J, Garí M, Wieser A, Eser TM, Frese J, Ahmed MIM, Rubio-Acero R, Guggenbuehl Noller JM, Castelletti N, Diekmannshemke J, Thiesbrummel S, Huynh D, Winter S, Kroidl I, Fuchs C, Hoelscher M, Roider J, Kobold S, Pritsch M, Geldmacher C. Brand I, et al. Among authors: eser tm. Front Immunol. 2021 May 20;12:688436. doi: 10.3389/fimmu.2021.688436. eCollection 2021. Front Immunol. 2021. PMID: 34093595 Free PMC article.