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Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Baden LR, El Sahly HM, Essink B, Kotloff K, Frey S, Novak R, Diemert D, Spector SA, Rouphael N, Creech CB, McGettigan J, Khetan S, Segall N, Solis J, Brosz A, Fierro C, Schwartz H, Neuzil K, Corey L, Gilbert P, Janes H, Follmann D, Marovich M, Mascola J, Polakowski L, Ledgerwood J, Graham BS, Bennett H, Pajon R, Knightly C, Leav B, Deng W, Zhou H, Han S, Ivarsson M, Miller J, Zaks T; COVE Study Group. Baden LR, et al. N Engl J Med. 2021 Feb 4;384(5):403-416. doi: 10.1056/NEJMoa2035389. Epub 2020 Dec 30. N Engl J Med. 2021. PMID: 33378609 Free PMC article. Clinical Trial.
Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase.
El Sahly HM, Baden LR, Essink B, Doblecki-Lewis S, Martin JM, Anderson EJ, Campbell TB, Clark J, Jackson LA, Fichtenbaum CJ, Zervos M, Rankin B, Eder F, Feldman G, Kennelly C, Han-Conrad L, Levin M, Neuzil KM, Corey L, Gilbert P, Janes H, Follmann D, Marovich M, Polakowski L, Mascola JR, Ledgerwood JE, Graham BS, August A, Clouting H, Deng W, Han S, Leav B, Manzo D, Pajon R, Schödel F, Tomassini JE, Zhou H, Miller J; COVE Study Group. El Sahly HM, et al. N Engl J Med. 2021 Nov 4;385(19):1774-1785. doi: 10.1056/NEJMoa2113017. Epub 2021 Sep 22. N Engl J Med. 2021. PMID: 34551225 Free PMC article. Clinical Trial.
Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity.
Pope WH, Bowman CA, Russell DA, Jacobs-Sera D, Asai DJ, Cresawn SG, Jacobs WR, Hendrix RW, Lawrence JG, Hatfull GF; Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science; Phage Hunters Integrating Research and Education; Mycobacterial Genetics Course. Pope WH, et al. Elife. 2015 Apr 28;4:e06416. doi: 10.7554/eLife.06416. Elife. 2015. PMID: 25919952 Free PMC article.
A Distinct Inhibitory Function for miR-18a in Th17 Cell Differentiation.
Montoya MM, Maul J, Singh PB, Pua HH, Dahlström F, Wu N, Huang X, Ansel KM, Baumjohann D. Montoya MM, et al. J Immunol. 2017 Jul 15;199(2):559-569. doi: 10.4049/jimmunol.1700170. Epub 2017 Jun 12. J Immunol. 2017. PMID: 28607111 Free PMC article.
In this study, we uncovered a distinct and critical role for miR-18a in limiting Th17 cell differentiation. miR-18a was the most dynamically upregulated microRNA of the miR-17-92 cluster in activated T cells. miR-18a deficiency enhanced CCR6(+) RAR-related orphan receptor …
In this study, we uncovered a distinct and critical role for miR-18a in limiting Th17 cell differentiation. miR-18a was the most dynamically …
Association of physical activity with vascular aging in a population with intermediate cardiovascular risk, analysis by sex: MARK study.
Gómez-Sánchez L, Rodríguez-Sánchez E, Ramos R, Marti R, Gómez-Sánchez M, Lugones-Sánchez C, Tamayo-Morales O, Sánchez SG, Rigo F, García-Ortiz L, Gómez-Marcos MA; MARK Investigators. Gómez-Sánchez L, et al. Biol Sex Differ. 2022 Aug 20;13(1):46. doi: 10.1186/s13293-022-00456-w. Biol Sex Differ. 2022. PMID: 35987700 Free PMC article.
Small RNA Transfection in Primary Human Th17 Cells by Next Generation Electroporation.
Montoya MM, Ansel KM. Montoya MM, et al. J Vis Exp. 2017 Apr 13;(122):55546. doi: 10.3791/55546. J Vis Exp. 2017. PMID: 28448060 Free PMC article.
CD4(+) T cells can differentiate into several subsets of effector T helper cells depending on the surrounding cytokine milieu. Th17 cells can be generated from naive CD4(+) T cells in vitro by activating them in the presence of the polarizing cytokines IL-1be …
CD4(+) T cells can differentiate into several subsets of effector T helper cells depending on the surrounding cytokine milieu. …
The Association Between the Cardio-ankle Vascular Index and Other Parameters of Vascular Structure and Function in Caucasian Adults: MARK Study.
Gomez-Sanchez L, Garcia-Ortiz L, Patino-Alonso MC, Recio-Rodriguez JI, Frontera G, Ramos R, Martí R, Agudo-Conde C, Rodriguez-Sanchez E, Maderuelo-Fernández JA, Gomez-Marcos MA; MARK Group. Gomez-Sanchez L, et al. J Atheroscler Thromb. 2015;22(9):901-11. doi: 10.5551/jat.28035. Epub 2015 May 20. J Atheroscler Thromb. 2015. PMID: 25994828 Free article.
Leukocyte subtype counts and its association with vascular structure and function in adults with intermediate cardiovascular risk. MARK study.
Gomez-Sanchez L, García-Ortiz L, Recio-Rodríguez JI, Patino-Alonso MC, Agudo-Conde C, Rigo F, Ramos R, Martí R, Gomez-Marcos MA; MARK Group. Gomez-Sanchez L, et al. PLoS One. 2015 Apr 17;10(4):e0119963. doi: 10.1371/journal.pone.0119963. eCollection 2015. PLoS One. 2015. PMID: 25885665 Free PMC article. Clinical Trial.
METHODS: This study analyzed 500 subjects who were included in the MARK study, aged 35 to 74 years (mean: 60.38.4), 45.6% women. MEASUREMENT: Brachial ankle Pulse Wave Velocity (ba-PWV) estimate by equation, Cardio-AnkleVascular Index (CAVI) using the VaSera device and Car …
METHODS: This study analyzed 500 subjects who were included in the MARK study, aged 35 to 74 years (mean: 60.38.4), 45.6% women. MEAS …