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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1975 6
1976 3
1977 3
1978 2
1979 4
1980 8
1981 32
1982 14
1983 19
1984 23
1985 22
1986 33
1987 25
1988 45
1989 63
1990 66
1991 57
1992 82
1993 64
1994 69
1995 84
1996 92
1997 100
1998 115
1999 128
2000 128
2001 145
2002 145
2003 157
2004 198
2005 196
2006 228
2007 225
2008 220
2009 269
2010 279
2011 301
2012 309
2013 334
2014 338
2015 300
2016 198
2017 182
2018 254
2019 204
2020 313
2021 287
2022 265
2023 240
2024 41

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6,225 results

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Page 1
A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model.
Kendirli A, de la Rosa C, Lämmle KF, Eglseer K, Bauer IJ, Kavaka V, Winklmeier S, Zhuo L, Wichmann C, Gerdes LA, Kümpfel T, Dornmair K, Beltrán E, Kerschensteiner M, Kawakami N. Kendirli A, et al. Nat Neurosci. 2023 Oct;26(10):1713-1725. doi: 10.1038/s41593-023-01432-2. Epub 2023 Sep 14. Nat Neurosci. 2023. PMID: 37709997 Free PMC article.
Here, we conducted a genome-wide in vivo CRISPR screen in a rat MS model and identified 5 essential brakes and 18 essential facilitators of T cell migration to the CNS. While the transcription factor ETS1 limits entry to the CNS by controlling T cell responsiveness, …
Here, we conducted a genome-wide in vivo CRISPR screen in a rat MS model and identified 5 essential brakes and 18 essential facilitators of …
Two novel cultured cell lines, A3/Kawakami and A4/Fukuda, derived from malignant lymphoma of B(non-T)-cell nature of the gastrointestinal tract.
Hirose M, Minato K, Tobinai K, Shimoyama M, Watanabe S, Abe T, Deura K. Hirose M, et al. Gan. 1983 Feb;74(1):106-15. Gan. 1983. PMID: 6601597
The fresh ascitic lymphoma cells in the case of A3/Kawakami were surface immunoglobulin-positive, but the cultured A3/Kawakami cells no longer expressed any distinct markers. ...It was found that monoclonal antibodies, OKT4 and anti-Leu 3a, which are known to react …
The fresh ascitic lymphoma cells in the case of A3/Kawakami were surface immunoglobulin-positive, but the cultured A3/Kawakami …
An autoimmunity odyssey: how autoreactive T cells infiltrate into the CNS.
Kawakami N, Bartholomäus I, Pesic M, Mues M. Kawakami N, et al. Immunol Rev. 2012 Jul;248(1):140-55. doi: 10.1111/j.1600-065X.2012.01133.x. Immunol Rev. 2012. PMID: 22725959 Review.
This interaction activates the T cells and guides them to penetrate the CNS parenchyma. As the local APCs in the CNS are not saturated with endogenous antigens, exogenous antigens stimulate the autoreactive T cells more strongly and, as a result, exacerbate the clin …
This interaction activates the T cells and guides them to penetrate the CNS parenchyma. As the local APCs in the CNS are not saturate …
Anaphylactic or tolerant outcomes with IgE.
Kawakami T, Kawakami Y. Kawakami T, et al. J Allergy Clin Immunol. 2020 Jan;145(1):114-115. doi: 10.1016/j.jaci.2019.10.017. Epub 2019 Oct 28. J Allergy Clin Immunol. 2020. PMID: 31672608 Free PMC article. No abstract available.
Human tumor antigens recognized by T-cells.
Kawakami Y, Rosenberg SA. Kawakami Y, et al. Immunol Res. 1997;16(4):313-39. doi: 10.1007/BF02786397. Immunol Res. 1997. PMID: 9439758 Review.
T-cells play an important role in in vivo tumor rejection in many animal tumor models and in human melanoma. ...A variety of mechanisms involved in generating these T-cell epitopes on growing cancers have also been identified. However, the role of these identified a …
T-cells play an important role in in vivo tumor rejection in many animal tumor models and in human melanoma. ...A variety of mechanis …
Regulatory T Cells for Control of Autoimmunity.
Kawakami R, Sakaguchi S. Kawakami R, et al. Adv Exp Med Biol. 2024;1444:67-82. doi: 10.1007/978-981-99-9781-7_5. Adv Exp Med Biol. 2024. PMID: 38467973
Regulatory T (Treg) cells, which specifically express the master transcription factor FoxP3, are indispensable for the maintenance of immunological self-tolerance and homeostasis. ...
Regulatory T (Treg) cells, which specifically express the master transcription factor FoxP3, are indispensable for the maintenance of …
Recent advances in mast cell activation and regulation.
Kim HS, Kawakami Y, Kasakura K, Kawakami T. Kim HS, et al. F1000Res. 2020 Mar 19;9:F1000 Faculty Rev-196. doi: 10.12688/f1000research.22037.1. eCollection 2020. F1000Res. 2020. PMID: 32226609 Free PMC article. Review.
Human tumor antigens recognized by T cells.
Robbins PF, Kawakami Y. Robbins PF, et al. Curr Opin Immunol. 1996 Oct;8(5):628-36. doi: 10.1016/s0952-7915(96)80078-1. Curr Opin Immunol. 1996. PMID: 8902387 Review.
The ability of tumor-reactive T cells to mediate in vivo tumor regression has been demonstrated in murine tumor models and by the clinical responses to adoptive immunotherapy with tumor-infiltrating lymphocytes isolated from human melanomas. Investigations carried out in t …
The ability of tumor-reactive T cells to mediate in vivo tumor regression has been demonstrated in murine tumor models and by the cli …
6,225 results