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Page 1
Glycemic Index, Glycemic Load, and Cardiovascular Disease and Mortality.
Jenkins DJA, Dehghan M, Mente A, Bangdiwala SI, Rangarajan S, Srichaikul K, Mohan V, Avezum A, Díaz R, Rosengren A, Lanas F, Lopez-Jaramillo P, Li W, Oguz A, Khatib R, Poirier P, Mohammadifard N, Pepe A, Alhabib KF, Chifamba J, Yusufali AH, Iqbal R, Yeates K, Yusoff K, Ismail N, Teo K, Swaminathan S, Liu X, Zatońska K, Yusuf R, Yusuf S; PURE Study Investigators. Jenkins DJA, et al. N Engl J Med. 2021 Apr 8;384(14):1312-1322. doi: 10.1056/NEJMoa2007123. Epub 2021 Feb 24. N Engl J Med. 2021. PMID: 33626252
Phase I/Phase II Study of Blinatumomab in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia.
von Stackelberg A, Locatelli F, Zugmaier G, Handgretinger R, Trippett TM, Rizzari C, Bader P, O'Brien MM, Brethon B, Bhojwani D, Schlegel PG, Borkhardt A, Rheingold SR, Cooper TM, Zwaan CM, Barnette P, Messina C, Michel G, DuBois SG, Hu K, Zhu M, Whitlock JA, Gore L. von Stackelberg A, et al. J Clin Oncol. 2016 Dec 20;34(36):4381-4389. doi: 10.1200/JCO.2016.67.3301. Epub 2016 Oct 31. J Clin Oncol. 2016. PMID: 27998223 Clinical Trial.
Purpose Blinatumomab is a bispecific T-cell engager antibody construct targeting CD19 on B-cell lymphoblasts. ...On the basis of the phase I data, the recommended blinatumomab dosage for children with relapsed/refractory ALL was 5 g/m(2)/d for the first 7 days, foll …
Purpose Blinatumomab is a bispecific T-cell engager antibody construct targeting CD19 on B-cell lymphoblasts. ...On the basis of the …
Molecular docking analysis of piperine with CDK2,CDK4,Cyclin D and Cyclin T proteins.
Rekha UV, Anita M, Jayamathi G, Sadhana K, Deepa S, Hussain S, Bhuvaneswari J, Ramya V, Selvaraj J, Naveenraj NS. Rekha UV, et al. Bioinformation. 2020 May 31;16(5):359-362. doi: 10.6026/97320630016359. eCollection 2020. Bioinformation. 2020. PMID: 32831516 Free PMC article.
Therefore, it is of interest to understand the molecular docking interactions of piperine with several cell cycle proteins such as Cyclin dependent kinase 2 (CDK2), Cyclin-dependent kinase 4 (CDK4), Cyclin D and Cyclin T for further consideration in drug discovery r …
Therefore, it is of interest to understand the molecular docking interactions of piperine with several cell cycle proteins such as Cyclin de …
Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma.
Thadathil N, Selvarani R, Mohammed S, Nicklas EH, Tran AL, Kamal M, Luo W, Brown JL, Lawrence MM, Borowik AK, Miller BF, Van Remmen H, Richardson A, Deepa SS. Thadathil N, et al. Aging Cell. 2022 Aug;21(8):e13676. doi: 10.1111/acel.13676. Epub 2022 Jul 23. Aging Cell. 2022. PMID: 35869934 Free PMC article.
D + Q treatment also reduced markers of inflammation in livers of the Sod1KO mice, for example, cytokines, chemokines, macrophage levels, and Kupffer cell clusters. ...Surprisingly, D + Q also reduced markers of necroptosis (phosphorylated and oligomerized MLKL) in …
D + Q treatment also reduced markers of inflammation in livers of the Sod1KO mice, for example, cytokines, chemokines, macrophage lev …
Activity determination and nuclear decay data of 177Lu.
Kossert K, Nähle OJ, Ott O, Dersch R. Kossert K, et al. Appl Radiat Isot. 2012 Sep;70(9):2215-21. doi: 10.1016/j.apradiso.2012.02.104. Epub 2012 Mar 4. Appl Radiat Isot. 2012. PMID: 22429554
The results are in good agreement with previous measurements at PTB but show a considerable discrepancy to recently published values from Deepa et al. (2011). The decay curve of a third solution was followed by liquid scintillation counting for about 66 days to determine t …
The results are in good agreement with previous measurements at PTB but show a considerable discrepancy to recently published values from …
Resonance assignment and secondary structure of the tandem harmonin homology domains of human RTEL1.
Kumar N, Ghosh M, Manikandan P, Basak S, Deepa A, Singh M. Kumar N, et al. Biomol NMR Assign. 2022 Apr;16(1):159-164. doi: 10.1007/s12104-022-10074-7. Epub 2022 Mar 23. Biomol NMR Assign. 2022. PMID: 35320499
It is a modular protein comprising an N-terminal helicase domain, two tandem harmonin homology domains 1 & 2 (HHD1 and HHD2), and a C-terminal C4C4 type RING domain. The N-terminal helicase domain disassembles the telomere t/D-loop and unwinds the G-quadruplex v …
It is a modular protein comprising an N-terminal helicase domain, two tandem harmonin homology domains 1 & 2 (HHD1 and HHD2), and a C-te …
Highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: insights into the sugar sequences with bioactivities.
Mizumoto S, Murakoshi S, Kalayanamitra K, Deepa SS, Fukui S, Kongtawelert P, Yamada S, Sugahara K. Mizumoto S, et al. Glycobiology. 2013 Feb;23(2):155-68. doi: 10.1093/glycob/cws137. Epub 2012 Sep 26. Glycobiology. 2013. PMID: 23019154
Seven novel hexasaccharide sequences, deltaO-D-D, deltaA-D-D, deltaC-D-D, deltaE-A-D, deltaD-D-C, deltaE-D-D and deltaA-B-D, in addition to three previously reported sequences, deltaC-A-D, deltaC- …
Seven novel hexasaccharide sequences, deltaO-D-D, deltaA-D-D, deltaC-D-D, deltaE-A-D, delta …
Antibacterial activities of 4-substituted-2-[(E)-{(1S,2R)/(1R,2S)-1-hydroxy-1-phenylpropan-2-ylimino}methyl]phenol.
Tamizh MM, Kesavan D, Sivakumar PM, Mereiter K, Deepa M, Kirchner K, Doble M, Karvembu R. Tamizh MM, et al. Chem Biol Drug Des. 2012 Feb;79(2):177-85. doi: 10.1111/j.1747-0285.2011.01263.x. Epub 2011 Nov 24. Chem Biol Drug Des. 2012. PMID: 22098701
A series of norephedrine-based Schiff bases (1a-6a and 1b-6b) were synthesized by reacting substituted salicylaldehydes with d-norephedrine or l-norephedrine. The structure of these compounds was confirmed by elemental analyses and spectroscopic techniques. ...
A series of norephedrine-based Schiff bases (1a-6a and 1b-6b) were synthesized by reacting substituted salicylaldehydes with d-noreph …
Tunable, conductive, self-healing, adhesive and injectable hydrogels for bioelectronics and tissue regeneration applications.
Panwar V, Babu A, Sharma A, Thomas J, Chopra V, Malik P, Rajput S, Mittal M, Guha R, Chattopadhyay N, Mandal D, Ghosh D. Panwar V, et al. J Mater Chem B. 2021 Aug 21;9(31):6260-6270. doi: 10.1039/d1tb01075a. Epub 2021 Aug 2. J Mater Chem B. 2021. PMID: 34338263
The porosity, rheological, mechanical and conductive properties of the hydrogels are regulated by the CMC-dialdehyde-polydopamine (CMC-D-PDA) content. The hydrogel was evaluated in various bioelectronics applications like ECG monitoring and triboelectric nanogenerators (TE …
The porosity, rheological, mechanical and conductive properties of the hydrogels are regulated by the CMC-dialdehyde-polydopamine (CMC-D …
35 results