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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 7
1976 6
1977 2
1978 9
1979 6
1980 10
1981 19
1982 21
1983 26
1984 39
1985 33
1986 40
1987 51
1988 52
1989 59
1990 44
1991 62
1992 53
1993 70
1994 73
1995 80
1996 60
1997 63
1998 81
1999 70
2000 66
2001 88
2002 94
2003 87
2004 94
2005 96
2006 106
2007 100
2008 122
2009 131
2010 117
2011 120
2012 149
2013 152
2014 182
2015 155
2016 137
2017 86
2018 131
2019 171
2020 160
2021 149
2022 143
2023 121
2024 29

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3,669 results

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Page 1
Showing results for T. brain cavity
Search for T. Brian Cavitt instead (3 results)
Sour Sensing from the Tongue to the Brain.
Zhang J, Jin H, Zhang W, Ding C, O'Keeffe S, Ye M, Zuker CS. Zhang J, et al. Cell. 2019 Oct 3;179(2):392-402.e15. doi: 10.1016/j.cell.2019.08.031. Epub 2019 Sep 19. Cell. 2019. PMID: 31543264 Free article.
The ability to sense sour provides an important sensory signal to prevent the ingestion of unripe, spoiled, or fermented foods. Taste and somatosensory receptors in the oral cavity trigger aversive behaviors in response to acid stimuli. Here, we show that the ion channel O …
The ability to sense sour provides an important sensory signal to prevent the ingestion of unripe, spoiled, or fermented foods. Taste and so …
Evaluation of intranasal delivery route of drug administration for brain targeting.
Erdő F, Bors LA, Farkas D, Bajza Á, Gizurarson S. Erdő F, et al. Brain Res Bull. 2018 Oct;143:155-170. doi: 10.1016/j.brainresbull.2018.10.009. Epub 2018 Oct 25. Brain Res Bull. 2018. PMID: 30449731 Free article. Review.
The reason of low brain penetration of the compounds is that they have to overcome the blood-brain barrier which protects the brain against xenobiotics. ...Furthermore, the drugs administered using nasal route have usually higher bioavailability, less side ef …
The reason of low brain penetration of the compounds is that they have to overcome the blood-brain barrier which protects the …
Nose-to-Brain Delivery.
Wang Z, Xiong G, Tsang WC, Schätzlein AG, Uchegbu IF. Wang Z, et al. J Pharmacol Exp Ther. 2019 Sep;370(3):593-601. doi: 10.1124/jpet.119.258152. Epub 2019 May 24. J Pharmacol Exp Ther. 2019. PMID: 31126978 Review.
The global prevalence of neurologic disorders is rising, and yet we are still unable to deliver most drug molecules, in therapeutic quantities, to the brain. The blood brain barrier consists of a tight layer of endothelial cells surrounded by astrocyte foot processe …
The global prevalence of neurologic disorders is rising, and yet we are still unable to deliver most drug molecules, in therapeutic quantiti …
Embryonic cerebrospinal fluid formation and regulation.
Bueno D, Parvas M, Nabiuni M, Miyan J. Bueno D, et al. Semin Cell Dev Biol. 2020 Jun;102:3-12. doi: 10.1016/j.semcdb.2019.09.006. Epub 2019 Oct 12. Semin Cell Dev Biol. 2020. PMID: 31615690 Review.
There is growing interest in the composition, dynamics and function of the CSF in brain development research. It has been demonstrated in higher vertebrates that CSF has key functions in delivering diffusible signals and nutrients to the developing brain, contributi …
There is growing interest in the composition, dynamics and function of the CSF in brain development research. It has been demonstrate …
Painful progress.
Pain S. Pain S. Nature. 2016 Jul 14;535(7611):S18-9. doi: 10.1038/535S18a. Nature. 2016. PMID: 27410528 No abstract available.
Cilia-driven flows in the brain third ventricle.
Eichele G, Bodenschatz E, Ditte Z, Günther AK, Kapoor S, Wang Y, Westendorf C. Eichele G, et al. Philos Trans R Soc Lond B Biol Sci. 2020 Feb 17;375(1792):20190154. doi: 10.1098/rstb.2019.0154. Epub 2019 Dec 30. Philos Trans R Soc Lond B Biol Sci. 2020. PMID: 31884922 Free PMC article. Review.
The brain ventricles are interconnected, elaborate cavities that traverse the brain. ...In particular, we consider the recently discovered intricate network of cilia-driven flows that characterize this ventricle and discuss the potential physiological signifi …
The brain ventricles are interconnected, elaborate cavities that traverse the brain. ...In particular, we consider the …
Innovative drug delivery strategies to the CNS for the treatment of multiple sclerosis.
Mwema A, Muccioli GG, des Rieux A. Mwema A, et al. J Control Release. 2023 Dec;364:435-457. doi: 10.1016/j.jconrel.2023.10.052. Epub 2023 Nov 8. J Control Release. 2023. PMID: 37926243 Review.
However, delivery of therapeutics to the CNS is mainly limited by the presence of the blood-brain barrier (BBB). Therefore, there is a pressing need to develop new drug delivery strategies that ensure CNS availability to capitalize on identified therapeutic targets. ...Amo …
However, delivery of therapeutics to the CNS is mainly limited by the presence of the blood-brain barrier (BBB). Therefore, there is …
Perspectives on brain-targeting drug delivery systems.
Guo L, Ren J, Jiang X. Guo L, et al. Curr Pharm Biotechnol. 2012 Sep;13(12):2310-8. doi: 10.2174/138920112803341770. Curr Pharm Biotechnol. 2012. PMID: 23016637 Review.
Due to the presence of the blood-brain barrier, there is limited drug access into the brain. In order to overcome this challenge, various strategies have been developed to enhance penetration of drugs into the brain. Of these, the most frequently used are pha …
Due to the presence of the blood-brain barrier, there is limited drug access into the brain. In order to overcome this challen …
Dendrimer-Based Drug Delivery Systems for Brain Targeting.
Zhu Y, Liu C, Pang Z. Zhu Y, et al. Biomolecules. 2019 Nov 27;9(12):790. doi: 10.3390/biom9120790. Biomolecules. 2019. PMID: 31783573 Free PMC article. Review.
Human neuroscience has made remarkable progress in understanding basic aspects of functional organization; it is a renowned fact that the blood-brain barrier (BBB) impedes the permeation and access of most drugs to central nervous system (CNS) and that many neurological di …
Human neuroscience has made remarkable progress in understanding basic aspects of functional organization; it is a renowned fact that the bl …
Nanoneurotherapeutics approach intended for direct nose to brain delivery.
Md S, Mustafa G, Baboota S, Ali J. Md S, et al. Drug Dev Ind Pharm. 2015;41(12):1922-34. doi: 10.3109/03639045.2015.1052081. Epub 2015 Jun 9. Drug Dev Ind Pharm. 2015. PMID: 26057769 Review.
However, intranasal administration produces quite low drug concentrations in the brain due limited nasal mucosal permeability and the harsh nasal cavity environment. ...The review discusses the role of nanotherapeutics in treating brain disorders via nose to …
However, intranasal administration produces quite low drug concentrations in the brain due limited nasal mucosal permeability and the …
3,669 results