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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 2
1978 1
1980 1
1981 1
1983 1
1984 1
1985 2
1986 3
1987 1
1988 5
1989 6
1990 3
1991 4
1992 8
1993 5
1994 9
1995 16
1996 26
1997 26
1998 24
1999 41
2000 27
2001 35
2002 50
2003 41
2004 60
2005 68
2006 53
2007 59
2008 89
2009 91
2010 111
2011 126
2012 154
2013 188
2014 201
2015 197
2016 117
2017 69
2018 95
2019 106
2020 122
2021 145
2022 91
2023 114
2024 18

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2,332 results

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Page 1
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry.
Tavernier N, Thomas Y, Vigneron S, Maisonneuve P, Orlicky S, Mader P, Regmi SG, Van Hove L, Levinson NM, Gasmi-Seabrook G, Joly N, Poteau M, Velez-Aguilera G, Gavet O, Castro A, Dasso M, Lorca T, Sicheri F, Pintard L. Tavernier N, et al. Nat Commun. 2021 Mar 26;12(1):1899. doi: 10.1038/s41467-021-21922-w. Nat Commun. 2021. PMID: 33771996 Free PMC article.
Plk1 is activated by phosphorylation on a conserved residue Thr210 in its activation segment by the Aurora A kinase (AURKA), a reaction that critically requires the co-factor Bora phosphorylated by a CyclinA/B-Cdk1 kinase. Here we show that phospho-Bora is a direct …
Plk1 is activated by phosphorylation on a conserved residue Thr210 in its activation segment by the Aurora A kinase (AURKA), a reaction that …
Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial.
Busse WW, Bleecker ER, FitzGerald JM, Ferguson GT, Barker P, Sproule S, Olsson RF, Martin UJ, Goldman M; BORA study investigators. Busse WW, et al. Lancet Respir Med. 2019 Jan;7(1):46-59. doi: 10.1016/S2213-2600(18)30406-5. Epub 2018 Nov 8. Lancet Respir Med. 2019. PMID: 30416083 Clinical Trial.
This endpoint was assessed in the full analysis set, which included all patients from the SIROCCO and CALIMA predecessor studies who received at least one dose of study treatment in BORA and did not continue into another trial. This study is registered with ClinicalTrials. …
This endpoint was assessed in the full analysis set, which included all patients from the SIROCCO and CALIMA predecessor studies who receive …
Imaging agents.
Chang CJ, Gunnlaugsson T, James TD. Chang CJ, et al. Chem Soc Rev. 2015 Jul 21;44(14):4484-6. doi: 10.1039/c5cs90065d. Chem Soc Rev. 2015. PMID: 26107987 No abstract available.
BODIPY-Based Molecules for Biomedical Applications.
Das S, Dey S, Patra S, Bera A, Ghosh T, Prasad B, Sayala KD, Maji K, Bedi A, Debnath S. Das S, et al. Biomolecules. 2023 Nov 30;13(12):1723. doi: 10.3390/biom13121723. Biomolecules. 2023. PMID: 38136594 Free PMC article. Review.
BODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) derivatives have attracted attention as probes in applications like imaging and sensing due to their unique properties like (1) strong absorption and emission in the visible and near-infrared regions of the electromagneti …
BODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) derivatives have attracted attention as probes in applications like imaging and s …
Bora and Aurora-A continue to activate Plk1 in mitosis.
Bruinsma W, Macurek L, Freire R, Lindqvist A, Medema RH. Bruinsma W, et al. J Cell Sci. 2014 Feb 15;127(Pt 4):801-11. doi: 10.1242/jcs.137216. Epub 2013 Dec 11. J Cell Sci. 2014. PMID: 24338364
Activation of Plk1 requires phosphorylation on a conserved threonine in the T-loop of the kinase domain (T210). Plk1 is first phosphorylated on T210 in G2 phase by the kinase Aurora-A, in concert with its cofactor Bora. ...Here we show that the Bora-Aurora-A …
Activation of Plk1 requires phosphorylation on a conserved threonine in the T-loop of the kinase domain (T210). Plk1 is first phospho …
Divergent reactivity of nucleophilic 1-bora-7a-azaindenide anions.
Morgan MM , Rautiainen JM , Piers WE , Tuononen HM , Gendy C . Morgan MM , et al. Dalton Trans. 2018 Jan 15;47(3):734-741. doi: 10.1039/c7dt04350c. Dalton Trans. 2018. PMID: 29239418
The reactions of 1-bora-7a-azaindenide anions, prepared in moderate to excellent yields by reduction of the appropriate 1-bora-7a-azaindenyl chlorides with KC(8) in THF, with alkyl halides and carbon dioxide were studied. ...Conversely, in the reaction of the 1-b …
The reactions of 1-bora-7a-azaindenide anions, prepared in moderate to excellent yields by reduction of the appropriate 1-bora …
Cdk1 Phosphorylates SPAT-1/Bora to Promote Plk1 Activation in C. elegans and Human Cells.
Thomas Y, Cirillo L, Panbianco C, Martino L, Tavernier N, Schwager F, Van Hove L, Joly N, Santamaria A, Pintard L, Gotta M. Thomas Y, et al. Cell Rep. 2016 Apr 19;15(3):510-518. doi: 10.1016/j.celrep.2016.03.049. Epub 2016 Apr 7. Cell Rep. 2016. PMID: 27068477 Free article.
The conserved Bora protein is a Plk1 activator, essential for checkpoint recovery after DNA damage in human cells. Here, we show that Bora interacts with Cyclin B and is phosphorylated by Cyclin B/Cdk1 at several sites. ...
The conserved Bora protein is a Plk1 activator, essential for checkpoint recovery after DNA damage in human cells. Here, we show that …
Fluorescent indicators based on BODIPY.
Boens N, Leen V, Dehaen W. Boens N, et al. Chem Soc Rev. 2012 Feb 7;41(3):1130-72. doi: 10.1039/c1cs15132k. Epub 2011 Jul 28. Chem Soc Rev. 2012. PMID: 21796324 Review.
This critical review covers the advances made using the 4-bora-3a,4a-diaza-s-indacene (BODIPY) scaffold as a fluorophore in the design, synthesis and application of fluorescent indicators for pH, metal ions, anions, biomolecules, reactive oxygen species, reactive nitrogen …
This critical review covers the advances made using the 4-bora-3a,4a-diaza-s-indacene (BODIPY) scaffold as a fluorophore in the desig …
Roadside sales activities in a South Pacific Island (Bora-Bora) reveal sustainable strategies for local food supply during a pandemic.
Minier L, Fourrière M, Gairin E, Gourlaouen A, Krimou S, Berthe C, Maueau T, Doom M, Sturny V, Mills SC, Lecchini D, Bertucci F. Minier L, et al. PLoS One. 2023 Apr 27;18(4):e0284276. doi: 10.1371/journal.pone.0284276. eCollection 2023. PLoS One. 2023. PMID: 37104283 Free PMC article.
People often returned to natural resources to provide for themselves, their families, or to generate income. On Bora-Bora Island, the major tourist destination in French Polynesia, roadside sales are widespread. ...Our results showed that the marketing system for lo …
People often returned to natural resources to provide for themselves, their families, or to generate income. On Bora-Bora Isla …
2,332 results