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Page 1
The Deubiquitinase OTUB1 Is a Key Regulator of Energy Metabolism.
Ruiz-Serrano A, Boyle CN, Monné Rodríguez JM, Günter J, Jucht AE, Pfundstein S, Bapst AM, Lutz TA, Wenger RH, Scholz CC. Ruiz-Serrano A, et al. Among authors: pfundstein s. Int J Mol Sci. 2022 Jan 28;23(3):1536. doi: 10.3390/ijms23031536. Int J Mol Sci. 2022. PMID: 35163456 Free PMC article.
OTUB1 regulates lung development, adult lung tissue homeostasis, and respiratory control.
Ruiz-Serrano A, Monné Rodríguez JM, Günter J, Sherman SPM, Jucht AE, Fluechter P, Volkova YL, Pfundstein S, Pellegrini G, Wagner CA, Schneider C, Wenger RH, Scholz CC. Ruiz-Serrano A, et al. Among authors: pfundstein s. FASEB J. 2021 Dec;35(12):e22039. doi: 10.1096/fj.202100346R. FASEB J. 2021. PMID: 34793600 Free article.
Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action.
Kast F, Schwill M, Stüber JC, Pfundstein S, Nagy-Davidescu G, Rodríguez JMM, Seehusen F, Richter CP, Honegger A, Hartmann KP, Weber TG, Kroener F, Ernst P, Piehler J, Plückthun A. Kast F, et al. Among authors: pfundstein s. Nat Commun. 2021 Jun 18;12(1):3790. doi: 10.1038/s41467-021-23948-6. Nat Commun. 2021. PMID: 34145240 Free PMC article.
The NO-donor MPC-1011 stimulates angiogenesis and arteriogenesis and improves hindlimb ischemia via a cGMP-dependent pathway involving VEGF and SDF-1α.
Gomes de Almeida Schirmer B, Crucet M, Stivala S, Vucicevic G, da Silva Barcelos L, Vanhoutte PM, Pellegrini G, Camici GG, Seebeck P, Pfundstein S, Stein S, Paneni F, Lüscher TF, Simic B. Gomes de Almeida Schirmer B, et al. Among authors: pfundstein s. Atherosclerosis. 2020 Jul;304:30-38. doi: 10.1016/j.atherosclerosis.2020.05.012. Epub 2020 May 30. Atherosclerosis. 2020. PMID: 32574829 Free article.
Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype.
Imeri F, Nolan KA, Bapst AM, Santambrogio S, Abreu-Rodríguez I, Spielmann P, Pfundstein S, Libertini S, Crowther L, Orlando IMC, Dahl SL, Keodara A, Kuo W, Kurtcuoglu V, Scholz CC, Qi W, Hummler E, Hoogewijs D, Wenger RH. Imeri F, et al. Among authors: pfundstein s. Kidney Int. 2019 Feb;95(2):375-387. doi: 10.1016/j.kint.2018.08.043. Epub 2018 Nov 27. Kidney Int. 2019. PMID: 30502050 Free article.