Differential regulation of IL-17A and IL-17F via STAT5 contributes to psoriatic disease.
Cole S, Manghera A, Burns L, Barrett J, Yager N, Rhys H, Skelton A, Cole J, Goodyear CS, Griffiths M, Baeten D, Bertolini M, Shaw S, Al-Mossawi H, Maroof A.
Cole S, et al.
J Allergy Clin Immunol. 2023 Sep;152(3):783-798. doi: 10.1016/j.jaci.2023.03.035. Epub 2023 May 25.
J Allergy Clin Immunol. 2023.
PMID: 37244461
OBJECTIVE: We characterized the regulation of IL-17A and IL-17F in psoriatic disease. METHODS: Using both in vitro systems and lesional skin tissue from patients, we interrogated the chromosomal, transcriptional, and protein expression landscape of IL-17A(+) and IL-17F(+) …
OBJECTIVE: We characterized the regulation of IL-17A and IL-17F in psoriatic disease. METHODS: Using both in vitro systems and lesional …