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Page 1
Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts.
Vermillion Maier ML, Siddens LK, Pennington JM, Uesugi SL, Tilton SC, Vertel EA, Anderson KA, Tidwell LG, Ognibene TJ, Turteltaub KW, Smith JN, Williams DE. Vermillion Maier ML, et al. Among authors: tilton sc. Toxicol Appl Pharmacol. 2023 Feb 1;460:116377. doi: 10.1016/j.taap.2023.116377. Epub 2023 Jan 13. Toxicol Appl Pharmacol. 2023. PMID: 36642108 Free PMC article. Clinical Trial.
Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [14C]-BaP.
Vermillion Maier ML, Siddens LK, Pennington JM, Uesugi SL, Anderson KA, Tidwell LG, Tilton SC, Ognibene TJ, Turteltaub KW, Smith JN, Williams DE. Vermillion Maier ML, et al. Among authors: tilton sc. Environ Int. 2022 Jan 15;159:107045. doi: 10.1016/j.envint.2021.107045. Epub 2021 Dec 15. Environ Int. 2022. PMID: 34920278 Free PMC article.
3,3'-Diindolylmethane Exhibits Significant Metabolism after Oral Dosing in Humans.
Vermillion Maier ML, Siddens LK, Uesugi SL, Choi J, Leonard SW, Pennington JM, Tilton SC, Smith JN, Ho E, Chow HHS, Nguyen BD, Kolluri SK, Williams DE. Vermillion Maier ML, et al. Among authors: tilton sc. Drug Metab Dispos. 2021 Aug;49(8):694-705. doi: 10.1124/dmd.120.000346. Epub 2021 May 25. Drug Metab Dispos. 2021. PMID: 34035125 Free PMC article.
Impact of phenanthrene co-administration on the toxicokinetics of benzo[a]pyrene in humans. UPLC-accelerator mass spectrometry following oral microdosing.
Maier MLV, Siddens LK, Pennington JM, Uesugi SL, Labut EM, Vertel EA, Anderson KA, Tidwell LG, Tilton SC, Ognibene TJ, Turteltaub KW, Smith JN, Williams DE. Maier MLV, et al. Among authors: tilton sc. Chem Biol Interact. 2023 Sep 1;382:110608. doi: 10.1016/j.cbi.2023.110608. Epub 2023 Jun 25. Chem Biol Interact. 2023. PMID: 37369263 Free PMC article.
Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing.
Madeen E, Siddens LK, Uesugi S, McQuistan T, Corley RA, Smith J, Waters KM, Tilton SC, Anderson KA, Ognibene T, Turteltaub K, Williams DE. Madeen E, et al. Among authors: tilton sc. Toxicol Appl Pharmacol. 2019 Feb 1;364:97-105. doi: 10.1016/j.taap.2018.12.010. Epub 2018 Dec 21. Toxicol Appl Pharmacol. 2019. PMID: 30582946 Free PMC article.
58 results