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Quantitative analysis of the major constituents in Chinese medicinal preparation SuoQuan formulae by ultra fast high performance liquid chromatography/quadrupole tandem mass spectrometry.
Chen F, Li HL, Li YH, Tan YF, Zhang JQ. Chen F, et al. Chem Cent J. 2013 Jul 30;7(1):131. doi: 10.1186/1752-153X-7-131. Chem Cent J. 2013. PMID: 23899222 Free PMC article.
BACKGROUND: The SuoQuan formulae containing Fructus Alpiniae Oxyphyllae has been used to combat the urinary incontinence symptoms including frequency, urgency and nocturia for hundreds of years in China. ...Furthermore, the significant content variation between the two dif …
BACKGROUND: The SuoQuan formulae containing Fructus Alpiniae Oxyphyllae has been used to combat the urinary incontinence symptoms inc …
Identification of known chemicals and their metabolites from Alpinia oxyphylla fruit extract in rat plasma using liquid chromatography/tandem mass spectrometry (LC-MS/MS) with selected reaction monitoring.
Chen F, Li HL, Tan YF, Li YH, Lai WY, Guan WW, Zhang JQ, Zhao YS, Qin ZM. Chen F, et al. J Pharm Biomed Anal. 2014 Aug;97:166-77. doi: 10.1016/j.jpba.2014.04.037. Epub 2014 May 10. J Pharm Biomed Anal. 2014. PMID: 24879483
This target analysis study revealed that: (1) low or trace plasma levels of parent chemicals were measured after p.o. administration of Yizhi extract, Suoquan capsules and pills to rats; (2) flavonoids and diarylheptanoids formed mainly monoglucuronide metabolites; however …
This target analysis study revealed that: (1) low or trace plasma levels of parent chemicals were measured after p.o. administration of Yizh …
Validated method to measure yakuchinone A in plasma by LC-MS/MS and its application to a pharmacokinetic study in rats.
Chen F, Li HL, Tan YF, Guan WW, Li YH, Zhang JQ. Chen F, et al. Chem Cent J. 2014 Jan 14;8(1):2. doi: 10.1186/1752-153X-8-2. Chem Cent J. 2014. PMID: 24422995 Free PMC article.
This new method was successfully applied to analyze the rat plasma concentration of parent yakuchinone A after a single oral administration of SuoQuan capsules. Low systemic exposure to parent yakuchinone A was observed. ...
This new method was successfully applied to analyze the rat plasma concentration of parent yakuchinone A after a single oral administration …