SUMO modification system facilitates the exchange of histone variant H2A.Z-2 at DNA damage sites.
Fukuto A, Ikura M, Ikura T, Sun J, Horikoshi Y, Shima H, Igarashi K, Kusakabe M, Harata M, Horikoshi N, Kurumizaka H, Kiuchi Y, Tashiro S.
Fukuto A, et al.
Nucleus. 2018 Jan 1;9(1):87-94. doi: 10.1080/19491034.2017.1395543. Epub 2017 Dec 14.
Nucleus. 2018.
PMID: 29095668
Free PMC article.
We previously demonstrated that the histone variant H2A.Z-2 is rapidly exchanged at damaged sites after DNA double strand break induction in human cells. In yeast, the small ubiquitin-like modifier (SUMO) modification of H2A.Z is involved in the DNA damage response. Howeve …
We previously demonstrated that the histone variant H2A.Z-2 is rapidly exchanged at damaged sites after DNA double strand break induction in …