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Did you mean sumin a (101 results)?
Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts.
Bhatt SP, Rabe KF, Hanania NA, Vogelmeier CF, Cole J, Bafadhel M, Christenson SA, Papi A, Singh D, Laws E, Mannent LP, Patel N, Staudinger HW, Yancopoulos GD, Mortensen ER, Akinlade B, Maloney J, Lu X, Bauer D, Bansal A, Robinson LB, Abdulai RM; BOREAS Investigators. Bhatt SP, et al. N Engl J Med. 2023 Jul 20;389(3):205-214. doi: 10.1056/NEJMoa2303951. Epub 2023 May 21. N Engl J Med. 2023. PMID: 37272521 Clinical Trial.
Voltage sensors of a Na(+) channel dissociate from the pore domain and form inter-channel dimers in the resting state.
Sumino A, Sumikama T, Shibata M, Irie K. Sumino A, et al. Nat Commun. 2023 Dec 19;14(1):7835. doi: 10.1038/s41467-023-43347-3. Nat Commun. 2023. PMID: 38114487 Free PMC article.
Understanding voltage-gated sodium (Na(v)) channels is significant since they generate action potential. Na(v) channels consist of a pore domain (PD) and a voltage sensor domain (VSD). ...
Understanding voltage-gated sodium (Na(v)) channels is significant since they generate action potential. Na(v) channels consis …
Incidence and risk factors of overcorrection in patients presenting with severe hyponatremia to the emergency department.
Sumi H, Imai N, Shibagaki Y. Sumi H, et al. Clin Exp Nephrol. 2022 Nov;26(11):1086-1091. doi: 10.1007/s10157-022-02252-7. Epub 2022 Jul 23. Clin Exp Nephrol. 2022. PMID: 35870090

METHODS: This is a single-center retrospective cohort study of 50 patients admitted through the emergency department with initial serum sodium (serum Na) < 125 mEq/L between January 2015 and December 2017. Incidence and risk factors of overcorrection and osmotic demyeli

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METHODS: This is a single-center retrospective cohort study of 50 patients admitted through the emergency department with initial serum sodi …
Pharmacological polysulfide suppresses glucose-stimulated insulin secretion in an ATP-sensitive potassium channel-dependent manner.
Shoji T, Hayashi M, Sumi C, Kusunoki M, Uba T, Matsuo Y, Kimura H, Hirota K. Shoji T, et al. Sci Rep. 2019 Dec 18;9(1):19377. doi: 10.1038/s41598-019-55848-7. Sci Rep. 2019. PMID: 31852936 Free PMC article.
In this study, we demonstrated that pharmacological polysulfide salts including Na(2)S(2), Na(2)S(3), and Na(2)S(4) considerably inhibit GSIS in mouse and rat pancreatic beta-cell-derived MIN6 and INS-1 cell lines, and that the effect is dependent on the acti …
In this study, we demonstrated that pharmacological polysulfide salts including Na(2)S(2), Na(2)S(3), and Na(2)S(4) con …
Effect of Fermentation Scale on Microbiota Dynamics and Metabolic Functions for Indigo Reduction.
Farjana N, Furukawa H, Sumi H, Yumoto I. Farjana N, et al. Int J Mol Sci. 2023 Sep 28;24(19):14696. doi: 10.3390/ijms241914696. Int J Mol Sci. 2023. PMID: 37834143 Free PMC article.
The correlation between indigo intensity reduction and metabolic functions suggests that V/A-type H(+)/Na(+)-transporting ATPase and NAD(P)H-producing enzymes drive membrane transportations and energization in the EET system, respectively....
The correlation between indigo intensity reduction and metabolic functions suggests that V/A-type H(+)/Na(+)-transporting ATPase and …
Ion Size Dependences of the Salting-Out Effect: Reversed Order of Sodium and Lithium Ions.
Katsuto H, Okamoto R, Sumi T, Koga K. Katsuto H, et al. J Phys Chem B. 2021 Jun 17;125(23):6296-6305. doi: 10.1021/acs.jpcb.1c03388. Epub 2021 Jun 8. J Phys Chem B. 2021. PMID: 34102058 Free article.
An exception is that Li(+), the smallest in alkali metal ions, has a notably weaker effect than Na(+). To understand the reversed order in the cation series, we performed molecular dynamics simulations of aqueous solutions of salt ions and calculated the Setschenow coeffic …
An exception is that Li(+), the smallest in alkali metal ions, has a notably weaker effect than Na(+). To understand the reversed ord …
Amitriptyline inhibits striatal efflux of neurotransmitters via blockade of voltage-dependent Na+ channels.
Ishii Y, Sumi T. Ishii Y, et al. Eur J Pharmacol. 1992 Oct 20;221(2-3):377-80. doi: 10.1016/0014-2999(92)90726-k. Eur J Pharmacol. 1992. PMID: 1358657
These effects of amitriptyline can be well explained by its blockade of voltage-dependent Na+ channels and may be independent of other activities of this drug such as re-uptake inhibition of monoamines and blockade of K+ channels....
These effects of amitriptyline can be well explained by its blockade of voltage-dependent Na+ channels and may be independent of othe …
The Patterns of Care Study and Regional Cancer Registry for non-small-cell lung cancer in Japan.
Sugiyama H, Teshima T, Ohno Y, Inoue T, Takahashi Y, Oshima A, Sumi M, Uno T, Ikeda H; Japanese PCS Working Subgroup for Lung Cancer. Sugiyama H, et al. Int J Radiat Oncol Biol Phys. 2003 Jul 15;56(4):1005-12. doi: 10.1016/s0360-3016(03)00215-3. Int J Radiat Oncol Biol Phys. 2003. PMID: 12829136

RESULTS: The mean age was 67.3 +/- 10.1 in PCS and 64.4 +/- 11.0 in OCR (p < 0.001), 67.2 in PCS NA. The male ratio was 84.2% in PCS and 84.0% in OCR (p = 0.411), 84.1% in PCS NA. The ratio of the patients at the localized stage was 24.2% in PCS and 15.6% in OCR

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RESULTS: The mean age was 67.3 +/- 10.1 in PCS and 64.4 +/- 11.0 in OCR (p < 0.001), 67.2 in PCS NA. The male ratio was 84.2% in P

…
Mutations in the human homologue of the Drosophila segment polarity gene patched in oral squamous cell carcinoma cell lines.
Michimukai E, Kitamura N, Zhang Y, Wang H, Hiraishi Y, Sumi K, Hayashido Y, Toratani S, Okamoto T. Michimukai E, et al. In Vitro Cell Dev Biol Anim. 2001 Jul-Aug;37(7):459-64. doi: 10.1290/1071-2690(2001)037<0459:mithho>2.0.co;2. In Vitro Cell Dev Biol Anim. 2001. PMID: 11573822
In addition, we demonstrated that the N-terminal fragment of sonic hedgehog (Shh-N) stimulates the growth of normal epithelial cells, the OSCC cell line, NA, and the salivary gland adenocarcinoma cell lines, HSG and HSY, which have no detectable mutation in patched. ...
In addition, we demonstrated that the N-terminal fragment of sonic hedgehog (Shh-N) stimulates the growth of normal epithelial cells, the OS …
32 results