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Page 1
S1P Lyase Deficiency in the Brain Promotes Astrogliosis and NLRP3 Inflammasome Activation via Purinergic Signaling.
Cells. 2023 Jul 13;12(14):1844. doi: 10.3390/cells12141844.
Cells. 2023.
PMID: 37508508
Free PMC article.
Sphingolipid metabolism in the development and progression of cancer: one cancer's help is another's hindrance.
Piazzesi A, Afsar SY, van Echten-Deckert G.
Piazzesi A, et al. Among authors: afsar sy.
Mol Oncol. 2021 Dec;15(12):3256-3279. doi: 10.1002/1878-0261.13063. Epub 2021 Jul 29.
Mol Oncol. 2021.
PMID: 34289244
Free PMC article.
Review.
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Synthesis and biological evaluation of simplified ajudazol derivatives reveal potent 5-lipoxygenase inhibition and considerable apoptotic activity in neuroblastoma cells.
Wollnitzke P, Wagner R, Afsar SY, Werner M, Geschold R, Müller CE, Werz O, van Echten-Deckert G, Menche D.
Wollnitzke P, et al. Among authors: afsar sy.
Bioorg Med Chem Lett. 2023 Oct 1;94:129464. doi: 10.1016/j.bmcl.2023.129464. Epub 2023 Aug 25.
Bioorg Med Chem Lett. 2023.
PMID: 37634760
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S1P Released by SGPL1-Deficient Astrocytes Enhances Astrocytic ATP Production via S1PR2,4, Thus Keeping Autophagy in Check: Potential Consequences for Brain Health.
Alam S, Afsar SY, Van Echten-Deckert G.
Alam S, et al. Among authors: afsar sy.
Int J Mol Sci. 2023 Feb 26;24(5):4581. doi: 10.3390/ijms24054581.
Int J Mol Sci. 2023.
PMID: 36902011
Free PMC article.
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