Domestically Acquired Seoul Virus Causing Hemophagocytic Lymphohistiocytosis-Washington, DC, 2018

Bhagyashree Shastri; Aaron Kofman; Andrew Hennenfent; John D Klena; Stuart Nicol; James C Graziano; Maria Morales-Betoulle; Deborah Cannon; Agueda Maradiaga; Anthony Tran; Sheena K Ramdeen

doi:10.1093/ofid/ofz404

Domestically Acquired Seoul Virus Causing Hemophagocytic Lymphohistiocytosis-Washington, DC, 2018

Open Forum Infect Dis. 2019 Sep 21;6(10):ofz404. doi: 10.1093/ofid/ofz404. eCollection 2019 Oct.

Affiliations

¹ Department of Infectious Diseases, Medstar Washington Hospital Center Atlanta, Georgia, USA, Washington, DC, USA.
² Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
³ Center for Policy, Planning and Evaluation, DC Department of Health, Washington, DC, USA.
⁴ Public Health Laboratory, DC Department of Forensic Sciences, Washington, DC, USA.

Abstract

Seoul orthohantavirus (SEOV) infections, uncommonly reported in the United States, often result in mild illness. We report a case of hemophagocytic lymphohistiocytosis secondary to SEOV infection that was domestically acquired in Washington, DC.

Keywords: hantavirus; hemophagocytic; hemorrhagic fever renal syndrome; lymphohistio- cytosis; seoul Virus.