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Page 1
Speed breeding orphan crops.
Theor Appl Genet. 2019 Mar;132(3):607-616. doi: 10.1007/s00122-018-3202-7. Epub 2018 Oct 19.
Theor Appl Genet. 2019.
PMID: 30341490
Review.
Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction.
Hardcastle IR, Ahmed SU, Atkins H, Calvert AH, Curtin NJ, Farnie G, Golding BT, Griffin RJ, Guyenne S, Hutton C, Källblad P, Kemp SJ, Kitching MS, Newell DR, Norbedo S, Northen JS, Reid RJ, Saravanan K, Willems HM, Lunec J.
Hardcastle IR, et al. Among authors: kemp sj.
Bioorg Med Chem Lett. 2005 Mar 1;15(5):1515-20. doi: 10.1016/j.bmcl.2004.12.061.
Bioorg Med Chem Lett. 2005.
PMID: 15713419
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Perennial Ryegrass Alkaloids Increase Respiration Rate and Decrease Plasma Prolactin in Merino Sheep under Both Thermoneutral and Mild Heat Conditions.
Henry MLE, Kemp S, Clarke IJ, Dunshea FR, Leury BJ.
Henry MLE, et al. Among authors: kemp s.
Toxins (Basel). 2019 Aug 19;11(8):479. doi: 10.3390/toxins11080479.
Toxins (Basel). 2019.
PMID: 31430938
Free PMC article.
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Small-molecule inhibitors of the MDM2-p53 protein-protein interaction based on an isoindolinone scaffold.
Hardcastle IR, Ahmed SU, Atkins H, Farnie G, Golding BT, Griffin RJ, Guyenne S, Hutton C, Källblad P, Kemp SJ, Kitching MS, Newell DR, Norbedo S, Northen JS, Reid RJ, Saravanan K, Willems HM, Lunec J.
Hardcastle IR, et al. Among authors: kemp sj.
J Med Chem. 2006 Oct 19;49(21):6209-21. doi: 10.1021/jm0601194.
J Med Chem. 2006.
PMID: 17034127
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Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein-protein interaction: structure-activity studies leading to improved potency.
Hardcastle IR, Liu J, Valeur E, Watson A, Ahmed SU, Blackburn TJ, Bennaceur K, Clegg W, Drummond C, Endicott JA, Golding BT, Griffin RJ, Gruber J, Haggerty K, Harrington RW, Hutton C, Kemp S, Lu X, McDonnell JM, Newell DR, Noble ME, Payne SL, Revill CH, Riedinger C, Xu Q, Lunec J.
Hardcastle IR, et al. Among authors: kemp s.
J Med Chem. 2011 Mar 10;54(5):1233-43. doi: 10.1021/jm1011929. Epub 2011 Feb 11.
J Med Chem. 2011.
PMID: 21314128
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Physiological Effects of Ergot Alkaloid and Indole-Diterpene Consumption on Sheep under Hot and Thermoneutral Ambient Temperature Conditions.
Henry ML, Kemp S, Dunshea FR, Leury BJ.
Henry ML, et al. Among authors: kemp s.
Animals (Basel). 2016 Jun 2;6(6):37. doi: 10.3390/ani6060037.
Animals (Basel). 2016.
PMID: 27271674
Free PMC article.
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Analysis of chemical shift changes reveals the binding modes of isoindolinone inhibitors of the MDM2-p53 interaction.
Riedinger C, Endicott JA, Kemp SJ, Smyth LA, Watson A, Valeur E, Golding BT, Griffin RJ, Hardcastle IR, Noble ME, McDonnell JM.
Riedinger C, et al. Among authors: kemp sj.
J Am Chem Soc. 2008 Nov 26;130(47):16038-44. doi: 10.1021/ja8062088.
J Am Chem Soc. 2008.
PMID: 18959403
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