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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2003 2
2004 2
2006 1
2007 1
2008 1
2009 2
2010 2
2011 2
2013 7
2014 4
2016 2
2017 1
2018 1
2019 3
2020 5
2021 6
2022 8
2023 9
2024 5

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56 results

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Page 1
The Search for Antidotes Against Ricin.
Botelho FD, Franca TCC, LaPlante SR. Botelho FD, et al. Among authors: laplante sr. Mini Rev Med Chem. 2024 Jan 23. doi: 10.2174/0113895575270509231121060105. Online ahead of print. Mini Rev Med Chem. 2024. PMID: 38350844
Revealing Drug Self-Associations into Nano-Entities.
Dlim MM, Shahout FS, Khabir MK, Labonté PP, LaPlante SR. Dlim MM, et al. Among authors: laplante sr. ACS Omega. 2019 May 23;4(5):8919-8925. doi: 10.1021/acsomega.9b00667. eCollection 2019 May 31. ACS Omega. 2019. PMID: 31459979 Free PMC article.
The challenge of atropisomerism in drug discovery.
Clayden J, Moran WJ, Edwards PJ, LaPlante SR. Clayden J, et al. Among authors: laplante sr. Angew Chem Int Ed Engl. 2009;48(35):6398-401. doi: 10.1002/anie.200901719. Angew Chem Int Ed Engl. 2009. PMID: 19637174 Review. No abstract available.
Jumping from Fragment to Drug via Smart Scaffolds.
Farahani MD, França TCC, Alapour S, Shahout F, Boulon R, Iddir M, Maddalena M, Ayotte Y, LaPlante SR. Farahani MD, et al. Among authors: laplante sr. ChemMedChem. 2022 May 18;17(10):e202200092. doi: 10.1002/cmdc.202200092. Epub 2022 Apr 1. ChemMedChem. 2022. PMID: 35298873
Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings.
Fnaiche A, Mélin L, Suárez NG, Paquin A, Vu V, Li F, Allali-Hassani A, Bolotokova A, Allemand F, Gelin M, Cotelle P, Woo S, LaPlante SR, Barsyte-Lovejoy D, Santhakumar V, Vedadi M, Guichou JF, Annabi B, Gagnon A. Fnaiche A, et al. Among authors: laplante sr. Bioorg Med Chem Lett. 2023 Oct 15;95:129488. doi: 10.1016/j.bmcl.2023.129488. Epub 2023 Sep 27. Bioorg Med Chem Lett. 2023. PMID: 37770003
Robust Strategy for Hit-to-Lead Discovery: NMR for SAR.
Larda ST, Ayotte Y, Denk MM, Coote P, Heffron G, Bendahan D, Shahout F, Girard N, Iddir M, Bouchard P, Bilodeau F, Woo S, Farmer LJ, LaPlante SR. Larda ST, et al. Among authors: laplante sr. J Med Chem. 2023 Oct 12;66(19):13416-13427. doi: 10.1021/acs.jmedchem.3c00656. Epub 2023 Sep 21. J Med Chem. 2023. PMID: 37732695 Free PMC article.
Searching for potential drugs against SARS-CoV-2 through virtual screening on several molecular targets.
Almeida JSFD, Botelho FD, de Souza FR, Dos Santos MC, Goncalves ADS, Rodrigues RLB, Cardozo M, Kitagawa DAS, Vieira LA, Silva RSF, Cavalcante SFA, Bastos LDC, Nogueira MOT, de Santana PIR, Brum JOC, Nepovimova E, Kuca K, LaPlante SR, Galante EBF, Franca TCC. Almeida JSFD, et al. Among authors: laplante sr. J Biomol Struct Dyn. 2022 Jul;40(11):5229-5242. doi: 10.1080/07391102.2020.1869096. Epub 2021 Jan 8. J Biomol Struct Dyn. 2022. PMID: 33416020 Free PMC article.
Development of LM98, a Small-Molecule TEAD Inhibitor Derived from Flufenamic Acid.
Mélin L, Abdullayev S, Fnaiche A, Vu V, González Suárez N, Zeng H, Szewczyk MM, Li F, Senisterra G, Allali-Hassani A, Chau I, Dong A, Woo S, Annabi B, Halabelian L, LaPlante SR, Vedadi M, Barsyte-Lovejoy D, Santhakumar V, Gagnon A. Mélin L, et al. Among authors: laplante sr. ChemMedChem. 2021 Oct 6;16(19):2982-3002. doi: 10.1002/cmdc.202100432. Epub 2021 Jul 28. ChemMedChem. 2021. PMID: 34164919
56 results