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Laboratory biomarkers associated with COVID-19 severity and management.
Keddie S, Ziff O, Chou MKL, Taylor RL, Heslegrave A, Garr E, Lakdawala N, Church A, Ludwig D, Manson J, Scully M, Nastouli E, Chapman MD, Hart M, Lunn MP. Keddie S, et al. Clin Immunol. 2020 Dec;221:108614. doi: 10.1016/j.clim.2020.108614. Epub 2020 Oct 22. Clin Immunol. 2020. PMID: 33153974 Free PMC article.
From analysis of 203 samples, CRP, IL-6, IL-10 and LDH were most strongly correlated with the WHO ordinal scale of illness severity, the fraction of inspired oxygen delivery, radiological evidence of ARDS and level of respiratory support (p 0.001). IL-6 levels of 3.27 pg/m …
From analysis of 203 samples, CRP, IL-6, IL-10 and LDH were most strongly correlated with the WHO ordinal scale of illness severity, the fra …
Impact of changes to the delivery of opioid agonist treatment, introduced during the COVID-19 pandemic, on treatment access and dropout in Ireland: An interrupted time series analysis.
Durand L, Boland F, Harnedy N, Delargy Í, Scully M, Bourke M, Ebbitt W, Otero Vázquez M, Keenan E, Cousins G. Durand L, et al. J Subst Use Addict Treat. 2023 Jun;149:209029. doi: 10.1016/j.josat.2023.209029. Epub 2023 Mar 31. J Subst Use Addict Treat. 2023. PMID: 37003538 Free PMC article.

RESULTS: A total of 10,251 people accessed OAT in Ireland in March 2019 (2 % buprenorphine, n = 178), increasing to 11,441 (4 % buprenorphine, n = 471) in March 2021. The study observed an immediate (beta(2) = 504.3, p < 0.001) and continued (beta(3) = 31.9, p &l

…
RESULTS: A total of 10,251 people accessed OAT in Ireland in March 2019 (2 % buprenorphine, n = 178), increasing to 11,441 (4 % buprenorphin …
Primary Melanoma of the Lung Treated with Surgery, Dabrafenib and Trametinib.
Landgraf LG, Malias MA, Patterson SJ. Landgraf LG, et al. Case Rep Oncol. 2020 Jul 7;13(2):789-792. doi: 10.1159/000508093. eCollection 2020 May-Aug. Case Rep Oncol. 2020. PMID: 32774277 Free PMC article.
Molecular testing (Caris Life Sciences) of the surgical tumor specimen revealed pathological BRAF DNA mutation in exon 15/p.V600K. The patient was initially treated with nivolumab, then treated with a combination of dabrafenib and trametinib at recurrence....
Molecular testing (Caris Life Sciences) of the surgical tumor specimen revealed pathological BRAF DNA mutation in exon 15/p.V600K. Th …
Genetic merit for fertility traits in Holstein cows: V. Factors affecting circulating progesterone concentrations.
Moore SG, Scully S, Browne JA, Fair T, Butler ST. Moore SG, et al. J Dairy Sci. 2014 Sep;97(9):5543-57. doi: 10.3168/jds.2014-8133. Epub 2014 Jun 18. J Dairy Sci. 2014. PMID: 24952779 Free article.
Progesterone concentrations were determined from d 0 to 9 (d 0=estrus) and on d 7, corpus luteum (CL) volume and blood flow area (BFA) were measured by B-mode and Doppler ultrasonography, respectively. Cows were administered PGF2alpha on d 7 in the p.m. and d 8 in the a.m. …
Progesterone concentrations were determined from d 0 to 9 (d 0=estrus) and on d 7, corpus luteum (CL) volume and blood flow area (BFA) were …
The long-term impact of diabetes on graft patency after coronary artery bypass grafting surgery: a substudy of the multicenter Radial Artery Patency Study.
Deb S, Singh SK, Moussa F, Tsubota H, Une D, Kiss A, Tomlinson G, Afshar M, Sless R, Cohen EA, Radhakrishnan S, Dubbin J, Schwartz L, Fremes SE; Radial Artery Patency Study Investigators. Deb S, et al. J Thorac Cardiovasc Surg. 2014 Oct;148(4):1246-53; discussion 1253. doi: 10.1016/j.jtcvs.2014.06.057. Epub 2014 Jul 17. J Thorac Cardiovasc Surg. 2014. PMID: 25109754 Free article. Clinical Trial.
In diabetic patients, the proportion of complete graft occlusion was significantly lower in the radial grafts (4/83 [4.8%]) than in the saphenous grafts (21/83 [25.3%]) (P=.0004), and this was similar in nondiabetic patients (P=.19). Multivariate modeling showed tha …
In diabetic patients, the proportion of complete graft occlusion was significantly lower in the radial grafts (4/83 [4.8%]) than in the saph …