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CDR132L improves systolic and diastolic function in a large animal model of chronic heart failure.
Batkai S, Genschel C, Viereck J, Rump S, Bär C, Borchert T, Traxler D, Riesenhuber M, Spannbauer A, Lukovic D, Zlabinger K, Hašimbegović E, Winkler J, Garamvölgyi R, Neitzel S, Gyöngyösi M, Thum T. Batkai S, et al. Among authors: rump s. Eur Heart J. 2021 Jan 7;42(2):192-201. doi: 10.1093/eurheartj/ehaa791. Eur Heart J. 2021. PMID: 33089304 Free PMC article.
Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study.
Täubel J, Hauke W, Rump S, Viereck J, Batkai S, Poetzsch J, Rode L, Weigt H, Genschel C, Lorch U, Theek C, Levin AA, Bauersachs J, Solomon SD, Thum T. Täubel J, et al. Among authors: rump s. Eur Heart J. 2021 Jan 7;42(2):178-188. doi: 10.1093/eurheartj/ehaa898. Eur Heart J. 2021. PMID: 33245749 Free PMC article. Clinical Trial.
Preclinical development of a miR-132 inhibitor for heart failure treatment.
Foinquinos A, Batkai S, Genschel C, Viereck J, Rump S, Gyöngyösi M, Traxler D, Riesenhuber M, Spannbauer A, Lukovic D, Weber N, Zlabinger K, Hašimbegović E, Winkler J, Fiedler J, Dangwal S, Fischer M, de la Roche J, Wojciechowski D, Kraft T, Garamvölgyi R, Neitzel S, Chatterjee S, Yin X, Bär C, Mayr M, Xiao K, Thum T. Foinquinos A, et al. Among authors: rump s. Nat Commun. 2020 Jan 31;11(1):633. doi: 10.1038/s41467-020-14349-2. Nat Commun. 2020. PMID: 32005803 Free PMC article.
Efficacy and safety of CDR132L in patients with reduced left ventricular ejection fraction after myocardial infarction: Rationale and design of the HF-REVERT trial.
Bauersachs J, Solomon SD, Anker SD, Antorrena-Miranda I, Batkai S, Viereck J, Rump S, Filippatos G, Granzer U, Ponikowski P, de Boer RA, Vardeny O, Hauke W, Thum T. Bauersachs J, et al. Among authors: rump s. Eur J Heart Fail. 2024 Mar;26(3):674-682. doi: 10.1002/ejhf.3139. Epub 2024 Jan 25. Eur J Heart Fail. 2024. PMID: 38269451 Clinical Trial.
Classical Xanthinuria in Nine Israeli Families and Two Isolated Cases from Germany: Molecular, Biochemical and Population Genetics Aspects.
Peretz H, Lagziel A, Bittner F, Kabha M, Shtauber-Naamati M, Zhuravel V, Usher S, Rump S, Wollers S, Bork B, Mandel H, Falik-Zaccai T, Kalfon L, Graessler J, Zeharia A, Heib N, Shalev H, Landau D, Levartovsky D. Peretz H, et al. Among authors: rump s. Biomedicines. 2021 Jul 7;9(7):788. doi: 10.3390/biomedicines9070788. Biomedicines. 2021. PMID: 34356852 Free PMC article.