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T lymphocytes induce human cancer cells derived from solid malignant tumors to secrete galectin-9 which facilitates immunosuppression in cooperation with other immune checkpoint proteins.
Schlichtner S, Yasinska IM, Lall GS, Berger SM, Ruggiero S, Cholewa D, Aliu N, Gibbs BF, Fasler-Kan E, Sumbayev VV. Schlichtner S, et al. Among authors: berger sm. J Immunother Cancer. 2023 Jan;11(1):e005714. doi: 10.1136/jitc-2022-005714. J Immunother Cancer. 2023. PMID: 36599470 Free PMC article.
Ligand-Receptor Interactions of Galectin-9 and VISTA Suppress Human T Lymphocyte Cytotoxic Activity.
Yasinska IM, Meyer NH, Schlichtner S, Hussain R, Siligardi G, Casely-Hayford M, Fiedler W, Wellbrock J, Desmet C, Calzolai L, Varani L, Berger SM, Raap U, Gibbs BF, Fasler-Kan E, Sumbayev VV. Yasinska IM, et al. Among authors: berger sm. Front Immunol. 2020 Nov 20;11:580557. doi: 10.3389/fimmu.2020.580557. eCollection 2020. Front Immunol. 2020. PMID: 33329552 Free PMC article.
Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 - Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes.
Schlichtner S, Yasinska IM, Ruggiero S, Berger SM, Aliu N, Prunk M, Kos J, Meyer NH, Gibbs BF, Fasler-Kan E, Sumbayev VV. Schlichtner S, et al. Among authors: berger sm. Front Med (Lausanne). 2022 Feb 10;9:790995. doi: 10.3389/fmed.2022.790995. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35223897 Free PMC article.
The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer.
Yasinska IM, Sakhnevych SS, Pavlova L, Teo Hansen Selnø A, Teuscher Abeleira AM, Benlaouer O, Gonçalves Silva I, Mosimann M, Varani L, Bardelli M, Hussain R, Siligardi G, Cholewa D, Berger SM, Gibbs BF, Ushkaryov YA, Fasler-Kan E, Klenova E, Sumbayev VV. Yasinska IM, et al. Among authors: berger sm. Front Immunol. 2019 Jul 11;10:1594. doi: 10.3389/fimmu.2019.01594. eCollection 2019. Front Immunol. 2019. PMID: 31354733 Free PMC article.
19 results