Masking of obstructive sleep apnoea by drug induced central sleep apnoea

Adv Respir Med. 2019;87(3):189-193. doi: 10.5603/ARM.2019.0030.

Abstract

Benzodiazepines are widely prescribed hypnotic agents which have multiple proven neurological and respiratory side effects. However, literature is sparse with regards to the incidence and occurrence of new onset central sleep apnoea in individuals being treated with benzodiazepines for insomnia. We present a case report of a patient presenting with new onset central sleep apnoea secondary to long term usage of benzodiazepines, with resultant masking of his pre-existing obstructive sleep apnoea.

Keywords: benzodiazepines; central sleep apnoea; obstructive sleep apnea.

Publication types

  • Case Reports

MeSH terms

  • Benzodiazepines / adverse effects*
  • Benzodiazepines / therapeutic use
  • Humans
  • Hypnotics and Sedatives / adverse effects*
  • Hypnotics and Sedatives / therapeutic use
  • Male
  • Middle Aged
  • Sleep Apnea, Central / chemically induced*
  • Sleep Apnea, Central / therapy
  • Sleep Initiation and Maintenance Disorders / drug therapy

Substances

  • Hypnotics and Sedatives
  • Benzodiazepines