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Page 1
Biallelic Mutations in P4HTM Cause Syndromic Obesity.
Saeed S, Ning L, Badreddine A, Mirza MU, Boissel M, Khanam R, Manzoor J, Janjua QM, Khan WI, Toussaint B, Vaillant E, Amanzougarene S, Derhourhi M, Trant JF, Siegert AM, Lam BYH, Yeo GSH, Chabraoui L, Touzani A, Kulkarni A, Farooqi IS, Bonnefond A, Arslan M, Froguel P. Saeed S, et al. Among authors: amanzougarene s. Diabetes. 2023 Sep 1;72(9):1228-1234. doi: 10.2337/db22-1017. Diabetes. 2023. PMID: 37083980
β-Cell-Specific E2f1 Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion.
Oger F, Bourouh C, Friano ME, Courty E, Rolland L, Gromada X, Moreno M, Carney C, Rabhi N, Durand E, Amanzougarene S, Berberian L, Derhourhi M, Blanc E, Hannou SA, Denechaud PD, Benfodda Z, Meffre P, Fajas L, Kerr-Conte J, Pattou F, Froguel P, Pourcet B, Bonnefond A, Collombat P, Annicotte JS. Oger F, et al. Among authors: amanzougarene s. Diabetes. 2023 Aug 1;72(8):1112-1126. doi: 10.2337/db22-0604. Diabetes. 2023. PMID: 37216637
Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming.
Oger F, Moreno M, Derhourhi M, Thiroux B, Berberian L, Bourouh C, Durand E, Amanzougarene S, Badreddine A, Blanc E, Molendi-Coste O, Pineau L, Pasquetti G, Rolland L, Carney C, Bornaque F, Courty E, Gheeraert C, Eeckhoute J, Dombrowicz D, Kerr-Conte J, Pattou F, Staels B, Froguel P, Bonnefond A, Annicotte JS. Oger F, et al. Among authors: amanzougarene s. iScience. 2023 Jun 30;26(7):107231. doi: 10.1016/j.isci.2023.107231. eCollection 2023 Jul 21. iScience. 2023. PMID: 37496675 Free PMC article.
TOGGLE: toolbox for generic NGS analyses.
Monat C, Tranchant-Dubreuil C, Kougbeadjo A, Farcy C, Ortega-Abboud E, Amanzougarene S, Ravel S, Agbessi M, Orjuela-Bouniol J, Summo M, Sabot F. Monat C, et al. Among authors: amanzougarene s. BMC Bioinformatics. 2015 Nov 9;16:374. doi: 10.1186/s12859-015-0795-6. BMC Bioinformatics. 2015. PMID: 26552596 Free PMC article.
Accuracy of RNAseq based SNP discovery and genotyping in Populusnigra.
Rogier O, Chateigner A, Amanzougarene S, Lesage-Descauses MC, Balzergue S, Brunaud V, Caius J, Soubigou-Taconnat L, Jorge V, Segura V. Rogier O, et al. Among authors: amanzougarene s. BMC Genomics. 2018 Dec 12;19(1):909. doi: 10.1186/s12864-018-5239-z. BMC Genomics. 2018. PMID: 30541448 Free PMC article.
Genetic Causes of Severe Childhood Obesity: A Remarkably High Prevalence in an Inbred Population of Pakistan.
Saeed S, Arslan M, Manzoor J, Din SM, Janjua QM, Ayesha H, Ain QT, Inam L, Lobbens S, Vaillant E, Durand E, Derhourhi M, Amanzougarene S, Badreddine A, Berberian L, Gaget S, Khan WI, Butt TA, Bonnefond A, Froguel P. Saeed S, et al. Among authors: amanzougarene s. Diabetes. 2020 Jul;69(7):1424-1438. doi: 10.2337/db19-1238. Epub 2020 Apr 29. Diabetes. 2020. PMID: 32349990
Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics.
Dance A, Fernandes J, Toussaint B, Vaillant E, Boutry R, Baron M, Loiselle H, Balkau B, Charpentier G, Franc S, Ibberson M, Marre M, Gernay M, Fadeur M, Paquot N, Vaxillaire M, Boissel M, Amanzougarene S, Derhourhi M, Khamis A, Froguel P, Bonnefond A. Dance A, et al. Among authors: amanzougarene s. Mol Metab. 2024 Jan;79:101867. doi: 10.1016/j.molmet.2023.101867. Epub 2023 Dec 28. Mol Metab. 2024. PMID: 38159881 Free PMC article.
Dominant PDX1 deficiency causes highly penetrant diabetes at different ages, associated with obesity and exocrine pancreatic deficiency: Lessons for precision medicine.
Kouidrat Y, Le Collen L, Vaxillaire M, Dechaume A, Toussaint B, Vaillant E, Amanzougarene S, Derhourhi M, Delemer B, Azahaf M, Froguel P, Bonnefond A. Kouidrat Y, et al. Among authors: amanzougarene s. Diabetes Metab. 2024 Jan;50(1):101507. doi: 10.1016/j.diabet.2023.101507. Epub 2023 Dec 21. Diabetes Metab. 2024. PMID: 38141807