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Year Number of Results
2002 1
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2013 3
2014 1
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Page 1
Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production.
Ito Y, Nakamura S, Sugimoto N, Shigemori T, Kato Y, Ohno M, Sakuma S, Ito K, Kumon H, Hirose H, Okamoto H, Nogawa M, Iwasaki M, Kihara S, Fujio K, Matsumoto T, Higashi N, Hashimoto K, Sawaguchi A, Harimoto KI, Nakagawa M, Yamamoto T, Handa M, Watanabe N, Nishi E, Arai F, Nishimura S, Eto K. Ito Y, et al. Among authors: nakamura s. Cell. 2018 Jul 26;174(3):636-648.e18. doi: 10.1016/j.cell.2018.06.011. Epub 2018 Jul 12. Cell. 2018. PMID: 30017246 Free article.
iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study.
Sugimoto N, Kanda J, Nakamura S, Kitano T, Hishizawa M, Kondo T, Shimizu S, Shigemasa A, Hirai H, Arai Y, Minami M, Tada H, Momose D, Koh KR, Nogawa M, Watanabe N, Okamoto S, Handa M, Sawaguchi A, Matsuyama N, Tanaka M, Hayashi T, Fuchizaki A, Tani Y, Takaori-Kondo A, Eto K. Sugimoto N, et al. Among authors: nakamura s. Blood. 2022 Dec 1;140(22):2398-2402. doi: 10.1182/blood.2022017296. Blood. 2022. PMID: 36112961 Free article. Clinical Trial. No abstract available.
Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells.
Nakamura S, Takayama N, Hirata S, Seo H, Endo H, Ochi K, Fujita K, Koike T, Harimoto K, Dohda T, Watanabe A, Okita K, Takahashi N, Sawaguchi A, Yamanaka S, Nakauchi H, Nishimura S, Eto K. Nakamura S, et al. Cell Stem Cell. 2014 Apr 3;14(4):535-48. doi: 10.1016/j.stem.2014.01.011. Epub 2014 Feb 13. Cell Stem Cell. 2014. PMID: 24529595 Free article.
Humanized mouse models with endogenously developed human natural killer cells for in vivo immunogenicity testing of HLA class I-edited iPSC-derived cells.
Flahou C, Morishima T, Higashi N, Hayashi Y, Xu H, Wang B, Zhang C, Ninomiya A, Qiu WY, Yuzuriha A, Suzuki D, Nakamura S, Manz M, Kaneko S, Hotta A, Takizawa H, Eto K, Sugimoto N. Flahou C, et al. Among authors: nakamura s. Biochem Biophys Res Commun. 2023 Jun 25;662:76-83. doi: 10.1016/j.bbrc.2023.04.067. Epub 2023 Apr 20. Biochem Biophys Res Commun. 2023. PMID: 37099813
A let-7 microRNA-RALB axis links the immune properties of iPSC-derived megakaryocytes with platelet producibility.
Chen SJ, Hashimoto K, Fujio K, Hayashi K, Paul SK, Yuzuriha A, Qiu WY, Nakamura E, Kanashiro MA, Kabata M, Nakamura S, Sugimoto N, Kaneda A, Yamamoto T, Saito H, Takayama N, Eto K. Chen SJ, et al. Among authors: nakamura s. Nat Commun. 2024 Mar 22;15(1):2588. doi: 10.1038/s41467-024-46605-0. Nat Commun. 2024. PMID: 38519457 Free PMC article.
Silencing of p53 and CDKN1A establishes sustainable immortalized megakaryocyte progenitor cells from human iPSCs.
Sone M, Nakamura S, Umeda S, Ginya H, Oshima M, Kanashiro MA, Paul SK, Hashimoto K, Nakamura E, Harada Y, Tsujimura K, Saraya A, Yamaguchi T, Sugimoto N, Sawaguchi A, Iwama A, Eto K, Takayama N. Sone M, et al. Among authors: nakamura s. Stem Cell Reports. 2021 Dec 14;16(12):2861-2870. doi: 10.1016/j.stemcr.2021.11.001. Epub 2021 Dec 2. Stem Cell Reports. 2021. PMID: 34861163 Free PMC article.
Production and nonclinical evaluation of an autologous iPSC-derived platelet product for the iPLAT1 clinical trial.
Sugimoto N, Nakamura S, Shimizu S, Shigemasa A, Kanda J, Matsuyama N, Tanaka M, Hayashi T, Fuchizaki A, Nogawa M, Watanabe N, Okamoto S, Handa M, Sawaguchi A, Momose D, Koh KR, Tani Y, Takaori-Kondo A, Eto K. Sugimoto N, et al. Among authors: nakamura s. Blood Adv. 2022 Dec 13;6(23):6056-6069. doi: 10.1182/bloodadvances.2022008512. Blood Adv. 2022. PMID: 36149941 Free PMC article.
25 results