Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug.
Nora GI, Venkatasubramanian R, Strindberg S, Siqueira-Jørgensen SD, Pagano L, Romanski FS, Swarnakar NK, Rades T, Müllertz A.
Nora GI, et al.
J Control Release. 2022 Sep;349:206-212. doi: 10.1016/j.jconrel.2022.06.057. Epub 2022 Jul 8.
J Control Release. 2022.
PMID: 35787914
Free article.
An ASD of ritonavir with polyvinylpyrrolidone-vinyl acetate copolymers (Kollidon VA64) was prepared by ball milling. Relevant control formulations, which include conventional SNEDDS (90% of S(eq)), superSNEDDS with a physical mix of Kollidon VA64 and ritonavir (superSNEDDS …
An ASD of ritonavir with polyvinylpyrrolidone-vinyl acetate copolymers (Kollidon VA64) was prepared by ball milling. Relevant control …