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Showing results for simian zheng
Search for Sixian Zheng instead (1 results)
Long-acting lenacapavir protects macaques against intravenous challenge with simian-tropic HIV.
Swanstrom AE, Gorelick RJ, Welker JL, Schmidt F, Lu B, Wang K, Rowe W, Breed MW, Killoran KE, Kramer JA, Donohue D, Roser JD, Bieniasz PD, Hatziioannou T, Pyle C, Thomas JA, Trubey CM, Zheng J, Blair W, Yant SR, Lifson JD, Del Prete GQ. Swanstrom AE, et al. EBioMedicine. 2023 Sep;95:104764. doi: 10.1016/j.ebiom.2023.104764. Epub 2023 Aug 23. EBioMedicine. 2023. PMID: 37625266 Free PMC article.
BACKGROUND: Long-acting subcutaneous lenacapavir (LEN), a first-in-class HIV capsid inhibitor approved by the US FDA for the treatment of multidrug-resistant HIV-1 with twice yearly dosing, is under investigation for HIV-1 pre-exposure prophylaxis (PrEP). We previously derived a …
BACKGROUND: Long-acting subcutaneous lenacapavir (LEN), a first-in-class HIV capsid inhibitor approved by the US FDA for the treatment of mu …
The nucleocytoplasmic transport of viral proteins.
Ding Q, Zhao L, Guo H, Zheng AC. Ding Q, et al. Virol Sin. 2010 Apr;25(2):79-85. doi: 10.1007/s12250-010-3099-z. Epub 2010 Apr 9. Virol Sin. 2010. PMID: 20960304 Free PMC article. Review.
Active transport of viral proteins is mediated by nuclear localization signals (NLS), which were first identified in Simian Virus 40 large T antigen and had subsequently been identified in a large number of viral proteins. ...
Active transport of viral proteins is mediated by nuclear localization signals (NLS), which were first identified in Simian Virus 40 …
RNA Landscapes of Brain and Brain-Derived Extracellular Vesicles in Simian Immunodeficiency Virus Infection and Central Nervous System Pathology.
Huang Y, Abdelgawad A, Turchinovich A, Queen S, Abreu CM, Zhu X, Batish M, Zheng L, Witwer KW. Huang Y, et al. J Infect Dis. 2024 May 15;229(5):1295-1305. doi: 10.1093/infdis/jiad563. J Infect Dis. 2024. PMID: 38079216
BACKGROUND: Brain tissue-derived extracellular vesicles (bdEVs) act locally in the central nervous system (CNS) and may indicate molecular mechanisms in human immunodeficiency virus (HIV) CNS pathology. Using brain homogenate (BH) and bdEVs from a simian immunodeficiency v …
BACKGROUND: Brain tissue-derived extracellular vesicles (bdEVs) act locally in the central nervous system (CNS) and may indicate molecular m …
Dual Simian Foamy Virus/Human Immunodeficiency Virus Type 1 Infections in Persons from Cote d'Ivoire.
Switzer WM, Tang S, Zheng H, Shankar A, Sprinkle PS, Sullivan V, Granade TC, Heneine W. Switzer WM, et al. PLoS One. 2016 Jun 16;11(6):e0157709. doi: 10.1371/journal.pone.0157709. eCollection 2016. PLoS One. 2016. PMID: 27310836 Free PMC article.
Zoonotic transmission of simian retroviruses in West-Central Africa occurring in primate hunters has resulted in pandemic spread of human immunodeficiency viruses (HIVs) and human T-lymphotropic viruses (HTLVs). While simian foamy virus (SFV) and simian T- ly …
Zoonotic transmission of simian retroviruses in West-Central Africa occurring in primate hunters has resulted in pandemic spread of h …
Long-acting capsid inhibitor protects macaques from repeat SHIV challenges.
Vidal SJ, Bekerman E, Hansen D, Lu B, Wang K, Mwangi J, Rowe W, Campigotto F, Zheng J, Kato D, Chandrashekar A, Barrett J, Patel S, Wan H, Anioke T, Mercado NB, Nkolola JP, Ferguson MJ, Rinaldi WJ, Callebaut C, Blair W, Cihlar T, Geleziunas R, Yant SR, Barouch DH. Vidal SJ, et al. Nature. 2022 Jan;601(7894):612-616. doi: 10.1038/s41586-021-04279-4. Epub 2021 Dec 7. Nature. 2022. PMID: 34875675 Free PMC article.
Here we show that a single subcutaneous administration of GS-CA1 provides long-term protection against repeated rectal simian-human immunodeficiency virus (SHIV) challenges in rhesus macaques. ...
Here we show that a single subcutaneous administration of GS-CA1 provides long-term protection against repeated rectal simian-human i …
HIV-1 Tat inhibits EAAT-2 through AEG-1 upregulation in models of HIV-associated neurocognitive disorder.
Ye X, Zhang Y, Xu Q, Zheng H, Wu X, Qiu J, Zhang Z, Wang W, Shao Y, Xing HQ. Ye X, et al. Oncotarget. 2017 Jun 13;8(24):39922-39934. doi: 10.18632/oncotarget.16485. Oncotarget. 2017. PMID: 28404980 Free PMC article. Review.
We used immunohistochemistry, western blot, qRT-PCR, and RNA interference to elucidate the molecular mechanisms underlying the decreased EAAT-2 expression during HAND at the tissue and cellular levels. We used simian immunodeficiency virus-human immunodeficiency virus chim …
We used immunohistochemistry, western blot, qRT-PCR, and RNA interference to elucidate the molecular mechanisms underlying the decreased EAA …
134 results