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Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic Malignancies.
ACS Med Chem Lett. 2020 Oct 14;11(12):2374-2381. doi: 10.1021/acsmedchemlett.0c00255. eCollection 2020 Dec 10.
ACS Med Chem Lett. 2020.
PMID: 33335659
Free PMC article.
Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases.
Murone M, Vaslin Chessex A, Attinger A, Ramachandra R, Shetty SJ, Daginakatte G, Sengupta S, Marappan S, Dhodheri S, Rigotti S, Bachhav Y, Brienza S, Traxler P, Lang M, Aguet M, Zoete V, Michielin O, Nicholas C, Johnson FM, Ramachandra M, McAllister A.
Murone M, et al. Among authors: marappan s.
Mol Cancer Ther. 2016 Oct;15(10):2334-2343. doi: 10.1158/1535-7163.MCT-15-0974. Epub 2016 Jul 20.
Mol Cancer Ther. 2016.
PMID: 27439479
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Novel CDK12/13 Inhibitors AU-15506 and AU-16770 Are Potent Anti-Cancer Agents in EGFR Mutant Lung Adenocarcinoma with and without Osimertinib Resistance.
Maity TK, Kim EY, Cultraro CM, Venugopalan A, Khare L, Poddutoori R, Marappan S, Syed SD, Telford WG, Samajdar S, Ramachandra M, Guha U.
Maity TK, et al. Among authors: marappan s.
Cancers (Basel). 2023 Apr 12;15(8):2263. doi: 10.3390/cancers15082263.
Cancers (Basel). 2023.
PMID: 37190191
Free PMC article.
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