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Did you mean sirna xia (1,663 results)?
CD177+ cells produce neutrophil extracellular traps that promote biliary atresia.
Zhang R, Su L, Fu M, Wang Z, Tan L, Chen H, Lin Z, Tong Y, Ma S, Ye R, Zhao Z, Wang Z, Chen W, Yu J, Zhong W, Zeng J, Liu F, Chai C, Guan X, Liu T, Liang J, Zhu Y, Gu X, Zhang Y, Lui VCH, Tam PKH, Lamb JR, Wen Z, Chen Y, Xia H. Zhang R, et al. J Hepatol. 2022 Nov;77(5):1299-1310. doi: 10.1016/j.jhep.2022.06.015. Epub 2022 Jul 5. J Hepatol. 2022. PMID: 35803543 Free article.
Neutrophil extracellular trap (NET) inhibitors were used to determine the role of CD177(+) cell-derived NETs in BA-associated bile duct damage, and a pilot clinical study evaluated the potential effects of N-acetylcysteine on NET release in BA. RESULTS: Increased levels of …
Neutrophil extracellular trap (NET) inhibitors were used to determine the role of CD177(+) cell-derived NETs in BA-associated bile duct dama …
Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes.
Qiu Z, He Y, Ming H, Lei S, Leng Y, Xia ZY. Qiu Z, et al. J Diabetes Res. 2019 Feb 17;2019:8151836. doi: 10.1155/2019/8151836. eCollection 2019. J Diabetes Res. 2019. PMID: 30911553 Free PMC article.
H9C2 cardiomyocytes were exposed to HG (30 mM) condition with or without LPS, along with caspase-1 inhibitor (Ac-YVAD-CMK), inflammasome inhibitor (BAY11-7082), ROS scavenger N-acetylcysteine (NAC), or not for 24 h, then subjected to 4 h of hypoxia followed by 2 h of reoxy …
H9C2 cardiomyocytes were exposed to HG (30 mM) condition with or without LPS, along with caspase-1 inhibitor (Ac-YVAD-CMK), inflammasome inh …
NUPR1 inhibitor ZZW-115 induces ferroptosis in a mitochondria-dependent manner.
Huang C, Santofimia-Castaño P, Liu X, Xia Y, Peng L, Gotorbe C, Neira JL, Tang D, Pouyssegur J, Iovanna J. Huang C, et al. Cell Death Discov. 2021 Oct 1;7(1):269. doi: 10.1038/s41420-021-00662-2. Cell Death Discov. 2021. PMID: 34599149 Free PMC article.
More importantly, we demonstrate that ZZW-115-induced mitochondrial morphological changes, compatible with the ferroptotic process, as well as mitochondrial network disorganization and strong mitochondrial metabolic dysfunction, which are rescued by both Fer-1 and N-acetylcyst …
More importantly, we demonstrate that ZZW-115-induced mitochondrial morphological changes, compatible with the ferroptotic process, as well …
Helicobacter pylori infection selectively attenuates endothelial function in male mice via exosomes-mediated ROS production.
Zhang L, Xia X, Wu H, Liu X, Zhu Q, Wang M, Hao H, Cui Y, Li DP, Chen SY, Martinez-Lemus LA, Hill MA, Xu C, Liu Z. Zhang L, et al. Front Cell Infect Microbiol. 2023 May 18;13:1142387. doi: 10.3389/fcimb.2023.1142387. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37274312 Free PMC article.
H. pylori infection attenuated acetylcholine (ACh)-induced endothelium-dependent aortic relaxation without changing nitroglycerine-induced endothelium-independent relaxation in male but not female mice, associated with increased ROS formation in aorta compared with controls, whic …
H. pylori infection attenuated acetylcholine (ACh)-induced endothelium-dependent aortic relaxation without changing nitroglycerine-induced e …
A prognostic evaluation and management of alcoholic hepatitis.
Rana R, Wang SL, Li J, Xia L, Song MY, Yang CQ. Rana R, et al. Minerva Med. 2017 Dec;108(6):554-567. doi: 10.23736/S0026-4806.17.05136-9. Epub 2017 Jun 9. Minerva Med. 2017. PMID: 28602070 Review.
Corticosteroid is the initial treatment of choice with infections screening before initiating; however, pentoxifylline is better preferred in case of AH with severe infections and hepatorenal syndrome. Additionally, combination of corticosteroids and N-acetylcysteine decre …
Corticosteroid is the initial treatment of choice with infections screening before initiating; however, pentoxifylline is better preferred i …
Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation.
Kusuyama J, Makarewicz NS, Albertson BG, Alves-Wagner AB, Conlin RH, Prince NB, Alves CRR, Ramachandran K, Kozuka C, Xiudong Y, Xia Y, Hirshman MF, Hatta T, Nagatomi R, Nozik ES, Goodyear LJ. Kusuyama J, et al. Diabetes. 2022 Jun 1;71(6):1170-1181. doi: 10.2337/db21-0706. Diabetes. 2022. PMID: 35290440 Free PMC article.
Placental superoxide dismutase 3 (SOD3), but not antioxidant treatment with N-acetylcysteine was necessary for the regulation of H3K4me3, gene expression, and glucose metabolism. ...
Placental superoxide dismutase 3 (SOD3), but not antioxidant treatment with N-acetylcysteine was necessary for the regulation of H3K4 …
Single cell RNA-sequencing analysis reveals that N-acetylcysteine partially reverses hepatic immune dysfunction in biliary atresia.
Ye R, Ma S, Chen Y, Shan J, Tan L, Su L, Tong Y, Zhao Z, Chen H, Fu M, Guo Z, Zuo X, Yu J, Zhong W, Zeng J, Liu F, Chai C, Guan X, Wang Z, Liu T, Liang J, Zhang Y, Shi H, Wen Z, Xia H, Zhang R. Ye R, et al. JHEP Rep. 2023 Sep 12;5(11):100908. doi: 10.1016/j.jhepr.2023.100908. eCollection 2023 Nov. JHEP Rep. 2023. PMID: 37869073 Free PMC article.
BACKGROUND & AIMS: Our previous study indicated that CD177(+) neutrophil activation has a vital role in the pathogenesis of biliary atresia (BA), which is partially ameliorated by N-acetylcysteine (NAC) treatment. Here, we evaluated the clinical efficacy of NAC treatme …
BACKGROUND & AIMS: Our previous study indicated that CD177(+) neutrophil activation has a vital role in the pathogenesis of biliary atre …
129 results