Recent Advances in Green Synthesis of Ag NPs for Extenuating Antimicrobial Resistance

Simerjeet Parmar; Harwinder Kaur; Jagpreet Singh; Avtar Singh Matharu; Seeram Ramakrishna; Mikhael Bechelany

doi:10.3390/nano12071115

Recent Advances in Green Synthesis of Ag NPs for Extenuating Antimicrobial Resistance

Nanomaterials (Basel). 2022 Mar 28;12(7):1115. doi: 10.3390/nano12071115.

Authors

Simerjeet Parmar¹, Harwinder Kaur¹, Jagpreet Singh^{2

3}, Avtar Singh Matharu⁴, Seeram Ramakrishna⁵, Mikhael Bechelany⁶

Affiliations

¹ Department of Biotechnology, Sri Guru Granth Sahib World University, Fatehgarh Sahib 140406, India.
² Department of Chemical Engineering, Chandigarh University, Gharuan, Mohali 140413, India.
³ University Centre for Research and Development, Chandigarh University, Gharuan, Mohali 140413, India.
⁴ Department of Chemistry, Green Chemistry Centre of Excellence, University of York, York YO10 5DD, UK.
⁵ Department of Mechanical Engineering, Centre for Nanotechnology & Sustainability, National University of Singapore, Singapore 117575, Singapore.
⁶ Institut Européen des Membranes, IEM, UMR 5635, University of Montpellier, ENSCM, CNRS, 34000 Montpellier, France.

Abstract

Combating antimicrobial resistance (AMR) is an on-going global grand challenge, as recognized by several UN Sustainable Development Goals. Silver nanoparticles (Ag NPs) are well-known for their efficacy against antimicrobial resistance, and a plethora of green synthesis methodologies now exist in the literature. Herein, this review evaluates recent advances in biological approaches for Ag NPs, and their antimicrobial potential of Ag NPs with mechanisms of action are explored deeply. Moreover, short and long-term potential toxic effects of Ag NPs on animals, the environment, and human health are briefly discussed. Finally, we also provide a summary of the current state of the research and future challenges on a biologically mediated Ag-nanostructures-based effective platform for alleviating AMR.

Keywords: antimicrobial resistance; environmental; green synthesis; silver NP’s.

Publication types

Review