Simeon Rüdesheim - Search Results

Year	Number of Results
2020	1
2021	1
2022	3
2023	2
2024	1

1

Physiologically based pharmacokinetic modeling of tacrolimus for food-drug and CYP3A drug-drug-gene interaction predictions.

Loer HLH, Feick D, Rüdesheim S, Selzer D, Schwab M, Teutonico D, Frechen S, van der Lee M, Moes DJAR, Swen JJ, Lehr T. Loer HLH, et al. Among authors: rudesheim s. CPT Pharmacometrics Syst Pharmacol. 2023 May;12(5):724-738. doi: 10.1002/psp4.12946. Epub 2023 Mar 10. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36808892 Free PMC article.

2

Physiologically-based pharmacokinetic modeling of quinidine to establish a CYP3A4, P-gp, and CYP2D6 drug-drug-gene interaction network.

Feick D, Rüdesheim S, Marok FZ, Selzer D, Loer HLH, Teutonico D, Frechen S, van der Lee M, Moes DJAR, Swen JJ, Schwab M, Lehr T. Feick D, et al. Among authors: rudesheim s. CPT Pharmacometrics Syst Pharmacol. 2023 Aug;12(8):1143-1156. doi: 10.1002/psp4.12981. Epub 2023 May 23. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37165978 Free PMC article.

3

Novel models for the prediction of drug-gene interactions.

Türk D, Fuhr LM, Marok FZ, Rüdesheim S, Kühn A, Selzer D, Schwab M, Lehr T. Türk D, et al. Among authors: rudesheim s. Expert Opin Drug Metab Toxicol. 2021 Nov;17(11):1293-1310. doi: 10.1080/17425255.2021.1998455. Epub 2021 Nov 15. Expert Opin Drug Metab Toxicol. 2021. PMID: 34727800

4

Physiologically-based pharmacokinetic modeling of dextromethorphan to investigate interindividual variability within CYP2D6 activity score groups.

Rüdesheim S, Selzer D, Fuhr U, Schwab M, Lehr T. Rüdesheim S, et al. CPT Pharmacometrics Syst Pharmacol. 2022 Apr;11(4):494-511. doi: 10.1002/psp4.12776. Epub 2022 Mar 8. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35257505 Free PMC article.

5

Prediction of Drug-Drug-Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling.

Kovar C, Kovar L, Rüdesheim S, Selzer D, Ganchev B, Kröner P, Igel S, Kerb R, Schaeffeler E, Mürdter TE, Schwab M, Lehr T. Kovar C, et al. Among authors: rudesheim s. Pharmaceutics. 2022 Nov 25;14(12):2604. doi: 10.3390/pharmaceutics14122604. Pharmaceutics. 2022. PMID: 36559098 Free PMC article.

6

Physiologically Based Pharmacokinetic Modeling to Describe the CYP2D6 Activity Score-Dependent Metabolism of Paroxetine, Atomoxetine and Risperidone.

Rüdesheim S, Selzer D, Mürdter T, Igel S, Kerb R, Schwab M, Lehr T. Rüdesheim S, et al. Pharmaceutics. 2022 Aug 18;14(8):1734. doi: 10.3390/pharmaceutics14081734. Pharmaceutics. 2022. PMID: 36015360 Free PMC article.

7

Physiologically based pharmacokinetic modeling of imatinib and N-desmethyl imatinib for drug-drug interaction predictions.

Loer HLH, Kovar C, Rüdesheim S, Marok FZ, Fuhr LM, Selzer D, Schwab M, Lehr T. Loer HLH, et al. Among authors: rudesheim s. CPT Pharmacometrics Syst Pharmacol. 2024 Mar 14. doi: 10.1002/psp4.13127. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38482980 Free article.

8

Physiologically Based Pharmacokinetic Modeling of Metoprolol Enantiomers and α-Hydroxymetoprolol to Describe CYP2D6 Drug-Gene Interactions.

Rüdesheim S, Wojtyniak JG, Selzer D, Hanke N, Mahfoud F, Schwab M, Lehr T. Rüdesheim S, et al. Pharmaceutics. 2020 Dec 11;12(12):1200. doi: 10.3390/pharmaceutics12121200. Pharmaceutics. 2020. PMID: 33322314 Free PMC article.

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