Risk factors and classification of stillbirth in a Middle Eastern population: a retrospective study

J Perinat Med. 2018 Nov 27;46(9):1022-1027. doi: 10.1515/jpm-2017-0274.

Abstract

Objective: To estimate the incidence of stillbirth, explore the associated maternal and fetal factors and to evaluate the most appropriate classification of stillbirth for a multiethnic population.

Methods: This is a retrospective population-based study of stillbirth in a large tertiary unit. Data of each stillbirth with a gestational age >/=24 weeks in the year 2015 were collected from electronic medical records and analyzed.

Results: The stillbirth rate for our multiethnic population is 7.81 per 1000 births. Maternal medical factors comprised 52.4% in which the rates of hypertensive disorders, diabetes and other medical disorders were 22.5%, 20.8% and 8.3%, respectively. The most common fetal factor was intrauterine growth restriction (IUGR) (22.5%) followed by congenital anomalies (21.6%). All cases were categorized using the Wigglesworth, Aberdeen, Tulip, ReCoDe and International Classification of Diseases-perinatal mortality (ICD-PM) classifications and the rates of unclassified stillbirths were 59.2%, 46.6%, 16.6%, 11.6% and 7.5%, respectively. An autopsy was performed in 9.1% of cases reflecting local religious and cultural sensitivities.

Conclusion: This study highlighted the modifiable risk factors among the Middle Eastern population. The most appropriate classification was the ICD-PM. The low rates of autopsy prevented a detailed evaluation of stillbirths, therefore it is suggested that a minimally invasive autopsy [postmortem magnetic resonance imaging (MRI)] may improve the quality of care.

Keywords: Classification; Middle East; incidence; risk factors; stillbirth.

MeSH terms

  • Adult
  • Diabetes Mellitus* / diagnosis
  • Diabetes Mellitus* / epidemiology
  • Ethnicity
  • Female
  • Fetal Growth Retardation / epidemiology
  • Gestational Age
  • Humans
  • Hypertension* / diagnosis
  • Hypertension* / epidemiology
  • Incidence
  • Infant, Newborn
  • Needs Assessment
  • Perinatal Mortality
  • Pregnancy
  • Pregnancy Complications* / diagnosis
  • Pregnancy Complications* / epidemiology
  • Prenatal Care / methods
  • Prenatal Care / statistics & numerical data
  • Qatar / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Stillbirth / epidemiology*