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Page 1
Cell-Autonomous Cxcl1 Sustains Tolerogenic Circuitries and Stromal Inflammation via Neutrophil-Derived TNF in Pancreatic Cancer.
Bianchi A, De Castro Silva I, Deshpande NU, Singh S, Mehra S, Garrido VT, Guo X, Nivelo LA, Kolonias DS, Saigh SJ, Wieder E, Rafie CI, Dosch AR, Zhou Z, Umland O, Amirian H, Ogobuiro IC, Zhang J, Ban Y, Shiau C, Nagathihalli NS, Montgomery EA, Hwang WL, Brambilla R, Komanduri K, Villarino AV, Toska E, Stanger BZ, Gabrilovich DI, Merchant NB, Datta J. Bianchi A, et al. Among authors: mehra s. Cancer Discov. 2023 Jun 2;13(6):1428-1453. doi: 10.1158/2159-8290.CD-22-1046. Cancer Discov. 2023. PMID: 36946782 Free PMC article.
Combined MEK and STAT3 Inhibition Uncovers Stromal Plasticity by Enriching for Cancer-Associated Fibroblasts With Mesenchymal Stem Cell-Like Features to Overcome Immunotherapy Resistance in Pancreatic Cancer.
Datta J, Dai X, Bianchi A, De Castro Silva I, Mehra S, Garrido VT, Lamichhane P, Singh SP, Zhou Z, Dosch AR, Messaggio F, Ban Y, Umland O, Hosein PJ, Nagathihalli NS, Merchant NB. Datta J, et al. Among authors: mehra s. Gastroenterology. 2022 Dec;163(6):1593-1612. doi: 10.1053/j.gastro.2022.07.076. Epub 2022 Aug 7. Gastroenterology. 2022. PMID: 35948109 Free PMC article.
Remodeling of Stromal Immune Microenvironment by Urolithin A Improves Survival with Immune Checkpoint Blockade in Pancreatic Cancer.
Mehra S, Garrido VT, Dosch AR, Lamichhane P, Srinivasan S, Singh SP, Zhou Z, De Castro Silva I, Joshi C, Ban Y, Datta J, Gilboa E, Merchant NB, Nagathihalli NS. Mehra S, et al. Cancer Res Commun. 2023 Jul 12;3(7):1224-1236. doi: 10.1158/2767-9764.CRC-22-0329. eCollection 2023 Jul. Cancer Res Commun. 2023. PMID: 37448553 Free PMC article.
Neutrophil-mediated fibroblast-tumor cell il-6/stat-3 signaling underlies the association between neutrophil-to-lymphocyte ratio dynamics and chemotherapy response in localized pancreatic cancer: A hybrid clinical-preclinical study.
de Castro Silva I, Bianchi A, Deshpande NU, Sharma P, Mehra S, Garrido VT, Saigh SJ, England J, Hosein PJ, Kwon D, Merchant NB, Datta J. de Castro Silva I, et al. Among authors: mehra s. Elife. 2022 Sep 15;11:e78921. doi: 10.7554/eLife.78921. Elife. 2022. PMID: 36107485 Free PMC article. Clinical Trial.
Hsp70 modulates immune response in pancreatic cancer through dendritic cells.
Giri B, Sharma P, Jain T, Ferrantella A, Vaish U, Mehra S, Garg B, Iyer S, Sethi V, Malchiodi Z, Signorelli R, Jacob HKC, George J, Sahay P, Bava EP, Dawra R, Ramakrishnan S, Saluja A, Dudeja V. Giri B, et al. Among authors: mehra s. Oncoimmunology. 2021 Sep 18;10(1):1976952. doi: 10.1080/2162402X.2021.1976952. eCollection 2021. Oncoimmunology. 2021. PMID: 34552825 Free PMC article.
Urolithin A attenuates severity of chronic pancreatitis associated with continued alcohol intake by inhibiting PI3K/AKT/mTOR signaling.
Mehra S, Srinivasan S, Singh S, Zhou Z, Garrido V, Silva IC, Totiger TM, Dosch AR, Dai X, Dawra RK, Jala VR, Shi C, Datta J, VanSaun M, Merchant N, Nagathihalli N. Mehra S, et al. Am J Physiol Gastrointest Liver Physiol. 2022 Oct 1;323(4):G375-G386. doi: 10.1152/ajpgi.00159.2022. Epub 2022 Sep 13. Am J Physiol Gastrointest Liver Physiol. 2022. PMID: 36098401 Free PMC article.
18 results