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Showing results for shukla promote
Search for Shukla Promite instead (2 results)
BCOR gene alterations in hematologic diseases.
Sportoletti P, Sorcini D, Falini B. Sportoletti P, et al. Blood. 2021 Dec 16;138(24):2455-2468. doi: 10.1182/blood.2021010958. Blood. 2021. PMID: 33945606 Free PMC article. Review.
These disruptive events lead to the loss of full-length BCOR protein and to the lack or low expression of a truncated form of the protein, both consistent with the tumor suppressor role of BCOR.BCOR and BCORL1 mutations are similar to those causing 2 rare X-linked diseases: oculo …
These disruptive events lead to the loss of full-length BCOR protein and to the lack or low expression of a truncated form of the protein, b …
Distinct designer diamines promote mitophagy, and thereby enhance healthspan in C. elegans and protect human cells against oxidative damage.
Srivastava V, Zelmanovich V, Shukla V, Abergel R, Cohen I, Ben-Sasson SA, Gross E. Srivastava V, et al. Autophagy. 2023 Feb;19(2):474-504. doi: 10.1080/15548627.2022.2078069. Epub 2022 Jun 1. Autophagy. 2023. PMID: 35579620 Free PMC article.
Based on the scaffold of spermidine (Spd), a known mitophagy-promoting agent, we designed and tested a family of structurally related compounds. ...Initial structural characterization suggests simple rules for the design of compounds with improved bioactivity, opening the …
Based on the scaffold of spermidine (Spd), a known mitophagy-promoting agent, we designed and tested a family of structurally related …
Antibody-Dependent Enhancement: A Challenge for Developing a Safe Dengue Vaccine.
Shukla R, Ramasamy V, Shanmugam RK, Ahuja R, Khanna N. Shukla R, et al. Front Cell Infect Microbiol. 2020 Oct 22;10:572681. doi: 10.3389/fcimb.2020.572681. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 33194810 Free PMC article. Review.
These antibodies are generally cross-reactive among DENV serotypes carrying a higher risk of promoting Antibody-Dependent Enhancement (ADE). ADE is a phenomenon in which suboptimal neutralizing or non-neutralizing cross-reactive antibodies bind to virus and facilitate Fcga …
These antibodies are generally cross-reactive among DENV serotypes carrying a higher risk of promoting Antibody-Dependent Enhancement …
Oncometabolite lactate enhances breast cancer progression by orchestrating histone lactylation-dependent c-Myc expression.
Pandkar MR, Sinha S, Samaiya A, Shukla S. Pandkar MR, et al. Transl Oncol. 2023 Nov;37:101758. doi: 10.1016/j.tranon.2023.101758. Epub 2023 Aug 10. Transl Oncol. 2023. PMID: 37572497 Free PMC article.
Due to the enhanced glycolytic rate, cancer cells generate lactate copiously, subsequently promoting the lactylation of histones. While previous studies have explored the impact of histone lactylation in modulating gene expression, the precise role of this epigenetic modif …
Due to the enhanced glycolytic rate, cancer cells generate lactate copiously, subsequently promoting the lactylation of histones. Whi …
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.
Hu T, Shukla SK, Vernucci E, He C, Wang D, King RJ, Jha K, Siddhanta K, Mullen NJ, Attri KS, Murthy D, Chaika NV, Thakur R, Mulder SE, Pacheco CG, Fu X, High RR, Yu F, Lazenby A, Steegborn C, Lan P, Mehla K, Rotili D, Chaudhary S, Valente S, Tafani M, Mai A, Auwerx J, Verdin E, Tuveson D, Singh PK. Hu T, et al. Gastroenterology. 2021 Nov;161(5):1584-1600. doi: 10.1053/j.gastro.2021.06.045. Epub 2021 Jul 8. Gastroenterology. 2021. PMID: 34245764 Free PMC article.
RESULTS: SIRT5 expression negatively regulated tumor cell proliferation and correlated with a favorable prognosis in patients with PDAC. Genetic ablation of Sirt5 in PDAC mouse models promoted acinar-to-ductal metaplasia, precursor lesions, and pancreatic tumorigenesis, re …
RESULTS: SIRT5 expression negatively regulated tumor cell proliferation and correlated with a favorable prognosis in patients with PDAC. Gen …
Boost Nature-Positive Production.
Hodson de Jaramillo E, Niggli U, Kitajima K, Lal R, Sadoff C. Hodson de Jaramillo E, et al. 2023 Jan 2. In: von Braun J, Afsana K, Fresco LO, Hassan MHA, editors. Science and Innovations for Food Systems Transformation [Internet]. Cham (CH): Springer; 2023. 2023 Jan 2. In: von Braun J, Afsana K, Fresco LO, Hassan MHA, editors. Science and Innovations for Food Systems Transformation [Internet]. Cham (CH): Springer; 2023. PMID: 38285826 Free Books & Documents. Review.
In: Climate Change and Land: an IPCC special report on climate change, desertification, land degradation, sustainable land management, food security, and greenhouse gas fluxes in terrestrial ecosystems [PR Shukla, J Skea, E Calvo Buendia, V Masson-Delmotte, H-O Portner, DC …
In: Climate Change and Land: an IPCC special report on climate change, desertification, land degradation, sustainable land management, food …
Host Molecules That Promote Pathophysiology of Ocular Herpes.
Shukla SD, Valyi-Nagy T. Shukla SD, et al. Front Microbiol. 2022 Jan 25;13:818658. doi: 10.3389/fmicb.2022.818658. eCollection 2022. Front Microbiol. 2022. PMID: 35145504 Free PMC article. Review.
In this review, we summarize the latest knowledge on host molecules that promote pathophysiological aspects of ocular herpes....
In this review, we summarize the latest knowledge on host molecules that promote pathophysiological aspects of ocular herpes....
Optineurin in ocular herpes infection.
Grinage E, Shukla D. Grinage E, et al. Exp Eye Res. 2022 Jun;219:109059. doi: 10.1016/j.exer.2022.109059. Epub 2022 Apr 4. Exp Eye Res. 2022. PMID: 35390332 Free PMC article. Review.
In recent years OPTN has gained increased attention because of its involvement in cellular mechanisms that promote homeostasis and prevent neurodegeneration. At the center of it all is the role OPTN plays as a receptor for selective autophagy. ...
In recent years OPTN has gained increased attention because of its involvement in cellular mechanisms that promote homeostasis and pr …
625 results