Abstract
In this research, three categories of phenylpropanoid glycosides (PPGs) were designed and synthesized with PPGs isolated from Rhodiola rosea L. as lead compounds. Their inhibitory abilities toward acetylcholinesterase (AChE) and xanthine oxidase (XOD) were also tested. Some of the synthetic PPGs exhibited excellent enzyme inhibitory abilities.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Acetylcholinesterase / metabolism*
-
Enzyme Inhibitors / chemical synthesis*
-
Enzyme Inhibitors / chemistry
-
Enzyme Inhibitors / pharmacology*
-
Glycosides / chemical synthesis*
-
Glycosides / chemistry
-
Glycosides / pharmacology*
-
Plant Extracts / chemistry*
-
Rhodiola / chemistry*
-
Xanthine Oxidase / antagonists & inhibitors
-
Xanthine Oxidase / metabolism*
Substances
-
Enzyme Inhibitors
-
Glycosides
-
Plant Extracts
-
Xanthine Oxidase
-
Acetylcholinesterase