A Highly Sensitive Nonenzymatic Glucose Biosensor Based on the Regulatory Effect of Glucose on Electrochemical Behaviors of Colloidal Silver Nanoparticles on MoS₂†

Kash Anderson; Benjamin Poulter; John Dudgeon; Shu-En Li; Xiang Ma

doi:10.3390/s17081807

A Highly Sensitive Nonenzymatic Glucose Biosensor Based on the Regulatory Effect of Glucose on Electrochemical Behaviors of Colloidal Silver Nanoparticles on MoS₂†

Sensors (Basel). 2017 Aug 5;17(8):1807. doi: 10.3390/s17081807.

Authors

Kash Anderson¹, Benjamin Poulter², John Dudgeon³, Shu-En Li⁴, Xiang Ma^{5

6}

Affiliations

¹ Department of Chemistry, Idaho State University, Pocatello, ID 83201, USA. andekas2@isu.edu.
² Department of Chemistry, Idaho State University, Pocatello, ID 83201, USA. poulbenj@isu.edu.
³ Department of Anthropology, Idaho State University, Pocatello, ID 83201, USA. dudgeon@isu.edu.
⁴ Department of Chemistry, Idaho State University, Pocatello, ID 83201, USA. lishue@isu.edu.
⁵ Department of Chemistry, Idaho State University, Pocatello, ID 83201, USA. maxian@isu.edu.
⁶ Present address: Department of Chemistry, Grand View University, Des Moines, IA 50316, USA. maxian@isu.edu.

Abstract

A novel and highly sensitive nonenzymatic glucose biosensor was developed by nucleating colloidal silver nanoparticles (AgNPs) on MoS₂. The facile fabrication method, high reproducibility (97.5%) and stability indicates a promising capability for large-scale manufacturing. Additionally, the excellent sensitivity (9044.6 μA mM^-1 cm^-2), low detection limit (0.03 μM), appropriate linear range of 0.1-1000 μM, and high selectivity suggests that this biosensor has a great potential to be applied for noninvasive glucose detection in human body fluids, such as sweat and saliva.

Keywords: colloidal silver nanoparticle; glucose biosensor; molybdenum disulfide; nonenzymatic.

MeSH terms

Biosensing Techniques*
Electrochemical Techniques
Electrodes
Glucose
Humans
Metal Nanoparticles
Reproducibility of Results
Silver

Substances

Silver
Glucose